Extracorporeal Irradiation of the Blood in Humans: Effects upon Erythrocyte Survival

Autor:	L. M. Schiffer, Horton A. Johnson, J. S. Robertson, Arjun D. Chanana, Pierre A. Stryckmans, Eugene P. Cronkite, Michael L. Greenberg, Harold L. Atkins
Rok vydání:	1966
Předmět:	Transplantation Red Cell business.industry Radiation dose Immunology Autologous erythrocytes Erythrocyte fragility Cell Biology Hematology Pharmacology medicine.disease Biochemistry Extracorporeal Hemolysis Leukemia Erythrocyte survival medicine Irradiation business
Zdroj:	Blood. 27:831-843
ISSN:	1528-0020 0006-4971
DOI:	10.1182/blood.v27.6.831.831
Popis:	Autologous erythrocytes were irradiated at doses of 35,000 to 200,000 rads, chromated, and red cell survival studied. The 24-hour loss of labeled cells and subsequent apparent erythrocyte survival times were found to be functions of the radiation dose. ECIB-produced red cell hemolysis of a mild degree is to be expected during courses of therapy, as demonstrated by clinical findings. However, there is no doubt that acute, severe, hemolysis could be produced by administering large doses to patients over a short period of time.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fc19802c47da122999fc576a61ea3d https://doi.org/10.1182/blood.v27.6.831.831 Zobrazit plný text záznamu