Feasibility of transrectal and transperineal fiducial marker placement for prostate cancer before proton therapy
| Autor: | K. Nakajima, Hiromitsu Iwata, Yuta Shibamoto, Jun-etsu Mizoe, Maho Yamada, Masashi Shimohira, Y. Hattori, Hiroyuki Ogino, Kengo Ohta, Shingo Hashimoto |
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| Rok vydání: | 2020 |
| Předmět: |
Male
Cancer Research medicine.medical_specialty medicine.medical_treatment Technical success Perineum Clinical success 030218 nuclear medicine & medical imaging 03 medical and health sciences Prostate cancer 0302 clinical medicine Fiducial Markers Proton Therapy medicine Humans Radiology Nuclear Medicine and imaging Major complication Proton therapy Aged Aged 80 and over Transperineal approach business.industry Rectum Prostatic Neoplasms General Medicine Middle Aged medicine.disease Radiation therapy Oncology 030220 oncology & carcinogenesis Feasibility Studies Radiology Fiducial marker business |
| Zdroj: | Japanese Journal of Clinical Oncology. 51:258-263 |
| ISSN: | 1465-3621 |
| DOI: | 10.1093/jjco/hyaa172 |
| Popis: | Background To compare the feasibility of transrectal and transperineal fiducial marker placement for prostate cancer before proton therapy. Materials and Methods From 2013 to 2015, the first 40 prostate cancer patients that were scheduled for proton therapy underwent transrectal fiducial marker placement, and the next 40 patients underwent transperineal fiducial marker placement (the first series). Technical and clinical success and pain scores were evaluated. In the second series (n = 280), the transrectal or transperineal approach was selected depending on the presence/absence of comorbidities, such as blood coagulation abnormalities. Seven patients refused to undergo the procedure. Thus, the total number of patients across both series was 353 (262 and 91 underwent the transrectal and transperineal approach, respectively). Technical and clinical success, complications, marker migration and the distance between the two markers were evaluated. Results In the first series, the technical and clinical success rates were 100% in both groups. The transrectal group exhibited lower pain scores than the transperineal group. The overall technical success rates of the transrectal and transperineal groups were 100% (262/262) and 99% (90/91), respectively (P > 0.05). The overall clinical success rate was 100% in both groups, and there were no major complications in either group. The migration rates of the two groups did not differ significantly. The mean distance between the two markers was 25.6 ± 7.1 mm (mean ± standard deviation) in the transrectal group and 31.9 ± 5.2 mm in the transperineal group (P Conclusion Both the transrectal and transperineal fiducial marker placement methods are feasible and safe. |
| Databáze: | OpenAIRE |
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