An International Collaborative Consensus Statement on En Bloc Resection of Bladder Tumour Incorporating Two Systematic Reviews, a Two-round Delphi Survey, and a Consensus Meeting

Autor: Lui-Shiong Lee, Steven MacLennan, Yong Wei, Thomas R. W. Herrmann, Jeremy Yuen-Chun Teoh, Hsiang-Ying Lee, Darren Ming-Chun Poon, Yuhong Yuan, Bernard Malavaud, Alberto Breda, Ronald C. K. Chan, Fernand Mac-Moune Lai, Hugh Mostafid, Vinson Wai-Shun Chan, Chun Pong Yu, Edmund Chiong, Chi-Fai Ng, Mario W. Kramer, Jun Miki, Wing-Kie Chow, Marek Babjuk
Rok vydání: 2020
Předmět:
Zdroj: EUROPEAN UROLOGY
r-IIB SANT PAU: Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
ISSN: 0302-2838
Popis: Background: There has been increasing interest in en bloc resection of bladder tumour (ERBT) as an oncologically noninferior alternative to transurethral resection of bladder tumour (TURBT) with fewer complications and better histology specimens. However, there is a lack of robust randomised controlled trial (RCT) data for making recommendations. Objective: We aimed to develop a consensus statement to standardise various aspects of ERBT for clinical practice and to guide future research. Design, setting, and participants: We developed the consensus statement on ERBT using a modified Delphi method. First, two systematic reviews were performed to investigate the clinical effectiveness of ERBT versus TURBT (effectiveness review) and to identify areas of uncertainty in ERBT (uncertainties review). Next, 200 health care professionals (urologists, oncologists, and pathologists) with experience in ERBT were invited to complete a two-round Delphi survey. Finally, a 16-member consensus panel meeting was held to review, discuss, and re-vote on the statements as appropriate. Outcome measurements and statistical analysis: Meta-analyses were performed for RCT data in the effectiveness review. Consensus statements were developed from the uncertainties review. Consensus was defined as follows: (1) >= 70% scoring a statement 7-9 and = 70% scoring a statement 1-3 and
Databáze: OpenAIRE