Construction of advanced producers of first- and second-generation ethanol in Saccharomyces cerevisiae and selected species of non-conventional yeasts (Scheffersomyces stipitis, Ogataea polymorpha)
Autor: | Olena O. Kurylenko, Justyna Ruchala, Kostyantyn V. Dmytruk, Andriy A. Sibirny |
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Rok vydání: | 2020 |
Předmět: |
Sucrose
Saccharomyces cerevisiae Bioethanol Bioengineering Xylose Ethanol fermentation Applied Microbiology and Biotechnology Pichia Metabolic engineering chemistry.chemical_compound Yeasts Animals Food science Bioenergy/Biofuels/Biochemicals - Review Ethanol biology Chemistry biology.organism_classification Yeast Glucose Biofuel Fermentation Alcoholic fermentation Ogataea polymorpha Biotechnology |
Zdroj: | Journal of Industrial Microbiology & Biotechnology |
ISSN: | 1476-5535 1367-5435 |
DOI: | 10.1007/s10295-019-02242-x |
Popis: | This review summarizes progress in the construction of efficient yeast ethanol producers from glucose/sucrose and lignocellulose. Saccharomyces cerevisiae is the major industrial producer of first-generation ethanol. The different approaches to increase ethanol yield and productivity from glucose in S. cerevisiae are described. Construction of the producers of second-generation ethanol is described for S. cerevisiae, one of the best natural xylose fermenters, Scheffersomyces stipitis and the most thermotolerant yeast known Ogataea polymorpha. Each of these organisms has some advantages and drawbacks. S. cerevisiae is the primary industrial ethanol producer and is the most ethanol tolerant natural yeast known and, however, cannot metabolize xylose. S. stipitis can effectively ferment both glucose and xylose and, however, has low ethanol tolerance and requires oxygen for growth. O. polymorpha grows and ferments at high temperatures and, however, produces very low amounts of ethanol from xylose. Review describes how the mentioned drawbacks could be overcome. |
Databáze: | OpenAIRE |
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