Post Autologous Stem Cell Transplantation Complication Management in Case of Malignant Lymphoma Patients
| Autor: | Annamária Pakucs, Erzsébet Lázár, Judit Beáta Köpeczi, Enikő Kakucs, István Benedek, Marius Găzdac, Eszter Mild, Cezara Tudor |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
autologous stem cell transplantation business.industry 030204 cardiovascular system & hematology Surgery Malignant lymphoma 03 medical and health sciences 0302 clinical medicine Autologous stem-cell transplantation 030220 oncology & carcinogenesis medicine Medicine malignant lymphoma complication management Complication business |
| Zdroj: | Journal of Interdisciplinary Medicine, Vol 2, Iss s4, Pp 36-38 (2017) |
| ISSN: | 2501-8132 |
| DOI: | 10.1515/jim-2017-0098 |
| Popis: | Introduction: Autologous hematopoietic stem cell transplantation (ASCT) represents a standard therapy in the management of hematologic malignancies such as malignant lymphomas and has used for approximately three decades. The aim of this study was to determine the occurring post-ASCT complications and their impact on the patients’ recovery for a better management. Material and methods: An observational retrospective study was performed during a five-year period between 2012 and 2017, involving 58 classical Hodgkin lymphoma and 36 non-Hodgkin lymphoma patients, who underwent ASCT in the Bone Marrow Transplantation Unit of Tîrgu Mureş. The main analyzed complications were: infections, bleeding, hydroelectrolytic disorders, and hypoalbuminemia. Results: After data analysis we found that 17 patients (18%) presented microbiologically confirmed infection, 10 patients (11%) presented clinically non-significant bleeding, 39 patients (42%) presented electrolyte disorders, and 33 patients (36%) presented hypoalbuminemia, obtaining a positive correlation between the rate of adverse events after ASCT with age (r = 0.9914, p = 0.0009) and the average hospitalization period (r = 1, p Conclusions: The identification of adverse events and their correlation with the patients’ clinical outcome can lead to better patient management and a faster recovery after ASCT. |
| Databáze: | OpenAIRE |
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