Transformation of Alkaloids of the Colchicine Type in Leaves and Flowers ofColchicum autumnaleandC. byzantinum
| Autor: | Vilím Šimánek, V. Preininger, H. Potěšilová, F. Šantavý |
|---|---|
| Rok vydání: | 1981 |
| Předmět: |
Pharmacology
biology Liliaceae Organic Chemistry Pharmaceutical Science biology.organism_classification Tropolone Analytical Chemistry Colchicum autumnale Transformation (genetics) chemistry.chemical_compound Colchicum byzantinum Complementary and alternative medicine chemistry Demecolcine Drug Discovery Botany Molecular Medicine Colchicine Enzymatic degradation |
| Zdroj: | Planta Medica. 43:153-160 |
| ISSN: | 1439-0221 0032-0943 |
| DOI: | 10.1055/s-2007-971492 |
| Popis: | It was found that the so far described variations in the content of colchicine alkaloids in leaves and flowers of Colchicum autumnale L. and C. byzantinum Ten. are due to enzymatic O-demethylation and degradation of colchicine (I), N-deacetyl-N-formylcolchicine (XI), and demecolcine (XVII) during drying and storing of the plant material. A simplified method was elaborated to separate the neutral, phenolic, basic, and basic-phenolic fractions of tropolone alkaloids. |
| Databáze: | OpenAIRE |
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