Evolution of Costs of Inflammatory Bowel Disease over Two Years of Follow-Up
| Autor: | Valk, M.E. van der, Mangen, M.J.J., Severs, M., Have, M. van der, Dijkstra, G., Bodegraven, A.A. van, Fidder, H.H., Jong, D.J. de, Woude, C.J. van der, Romberg-Camps, M.J.L., Clemens, C.H.M., Jansen, J.M., Meeberg, P.C.V. de, Mahmmod, N., Meulen-de Jong, A.E. van der, Ponsioen, C.Y., Bolwerk, C., Vermeijden, J.R., Siersema, P.D., Leenders, M., Oldenburg, B., COIN Study Grp, Dutch Initiative Crohn Colitis |
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| Přispěvatelé: | Gastroenterology & Hepatology, Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Translational Immunology Groningen (TRIGR), Groningen Institute for Organ Transplantation (GIOT), AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Gastroenterology and Hepatology, Gastroenterology and hepatology, Surgery |
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Male
Questionnaires Economics Total cost CLINICAL-COURSE POPULATION-BASED COHORT Social Sciences lcsh:Medicine Crohn's Disease Logistic regression HEALTH-CARE COSTS Inflammatory bowel disease Tumours of the digestive tract Radboud Institute for Health Sciences [Radboudumc 14] Mathematical and Statistical Techniques 0302 clinical medicine Surveys and Questionnaires SWEDEN Medicine and Health Sciences Medicine Non-U.S. Gov't lcsh:Science PREDICTORS health care economics and organizations Crohn's disease Multidisciplinary Research Support Non-U.S. Gov't Health Care Costs Middle Aged Colitis Ulcerative colitis CROHNS-DISEASE Abdominal Surgery ULCERATIVE-COLITIS Research Design 030220 oncology & carcinogenesis Physical Sciences INCEPTION COHORT Regression Analysis Female 030211 gastroenterology & hepatology Statistics (Mathematics) Research Article medicine.medical_specialty Immunology Surgical and Invasive Medical Procedures Other Research Radboud Institute for Molecular Life Sciences [Radboudumc 0] Gastroenterology and Hepatology ILLNESS Research and Analysis Methods Research Support Autoimmune Diseases 03 medical and health sciences Health Economics Pharmacotherapy Internal medicine Journal Article Humans Ulcerative Colitis Statistical Methods Survey Research Health economics Tumor Necrosis Factor-alpha business.industry Inflammatory Bowel Disease lcsh:R Biology and Life Sciences Odds ratio Inflammatory Bowel Diseases medicine.disease Surgery RHEUMATOID-ARTHRITIS Health Care Logistic Models Clinical Immunology lcsh:Q Clinical Medicine business Delivery of Health Care Mathematics Follow-Up Studies |
| Zdroj: | PLoS ONE, Vol 11, Iss 4, p e0142481 (2016) PLoS One, 11, 4 PLoS ONE PLoS ONE, 11(4). PUBLIC LIBRARY SCIENCE van der Valk, M E, Mangen, M-J J, Severs, M, van der Have, M, Dijkstra, G, van Bodegraven, A A, Fidder, H H, de Jong, D J, van der Woude, C J, Romberg-Camps, M J L, Clemens, C H M, Jansen, J M, de Meeberg, P C V, Mahmmod, N, van der Meulen-de Jong, A E, Ponsioen, C Y, Bolwerk, C, Vermeijden, J R, Siersema, P D, Leenders, M & Oldenburg, B 2016, ' Evolution of Costs of Inflammatory Bowel Disease over Two Years of Follow-Up ', PLoS ONE, vol. 11, no. 4 . https://doi.org/10.1371/journal.pone.0142481 PLoS ONE [E], 11(4). Public Library of Science PLoS One, 11 PLoS One (print), 11(4). Public Library of Science PLoS ONE, 11(4):e0142481. PUBLIC LIBRARY SCIENCE PLoS ONE, 11(4). Public Library of Science |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0142481 |
| Popis: | Contains fulltext : 172504.PDF (Publisher’s version ) (Open Access) BACKGROUND: With the increasing use of anti-TNF therapy in inflammatory bowel disease (IBD), a shift of costs has been observed with medication costs replacing hospitalization and surgery as major cost driver. We aimed to explore the evolution of IBD-related costs over two years of follow-up. METHODS AND FINDINGS: In total 1,307 Crohn's disease (CD) patients and 915 ulcerative colitis (UC) patients were prospectively followed for two years by three-monthly web-based questionnaires. Changes of healthcare costs, productivity costs and out-of-pocket costs over time were assessed using mixed model analysis. Multivariable logistic regression analysis was used to identify costs drivers. In total 737 CD patients and 566 UC were included. Total costs were stable over two years of follow-up, with annual total costs of euro7,835 in CD and euro3,600 in UC. However, within healthcare costs, the proportion of anti-TNF therapy-related costs increased from 64% to 72% in CD (p |
| Databáze: | OpenAIRE |
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