Hypercholesterolemia in renal allograft recipients Comparison with non-renal hypercholesterolemia and normal subjects
| Autor: | Lynn K. Abbott, Christine Elliott, Janet M. Aitken, John B. Somer |
|---|---|
| Rok vydání: | 1978 |
| Předmět: |
Very low-density lipoprotein
medicine.medical_specialty Hypercholesterolemia Phospholipid Lipoproteins VLDL chemistry.chemical_compound Free cholesterol Internal medicine Hyperlipidemia Humans Transplantation Homologous Medicine Phospholipids Triglycerides Triglyceride business.industry Hypertriglyceridemia medicine.disease Kidney Transplantation Lipoproteins LDL Cholesterol Endocrinology chemistry Cholesteryl ester Female lipids (amino acids peptides and proteins) Lipoproteins HDL Cardiology and Cardiovascular Medicine business Lipoprotein |
| Zdroj: | Atherosclerosis. 30:255-262 |
| ISSN: | 0021-9150 |
| Popis: | In order to investigate the degree of similarity between renal transplant and non-renal hypercholesterolemia, serum and lipoprotein lipid compositions were compared in female transplant hypercholesterolemic patients (serum cholesterol greater than 240 mg/100 ml, serum triglyceride less than 150 mg/100 ml) and female non-renal hypercholesterolemic and normal subjects. A number of lipid abnormalities were demonstrated: (1) Serum and LDL cholesterol and phospholipid levels were significantly elevated in both transplant and non-renal hypercholesterolemic patients; (2) Serum triglyceride, VLDL cholesterol, triglyceride and phospholipid, and LDL and HDL triglyceride were significantly increased in transplant hypercholesterolemic patients. Changes of this nature are usually found in hypertriglyceridemia, and were not observed in non-renal hypercholesterolemic subjects. Finally, a number of changes in the ratio of esterified to free cholesterol and in the ratios of other lipoprotein-lipids, most of which did not correspond to any changes found in the common non-renal hyperlipidemias, were also demonstrated. |
| Databáze: | OpenAIRE |
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