Autor: |
Lucio Urbani, Nicolò Roffi, Stefano Signori, Riccardo Balestri, Piero Colombatto, Gabriella Licitra, Chiara Leoni, Daniele Meiattini, Roberto Moretto, Chiara Cremolini, Gianluca Masi, Piero Boraschi, Francesca Quilici, Piero Buccianti, Marco Puccini |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
Langenbeck's Archives of Surgery. 407:1741-1750 |
ISSN: |
1435-2451 |
DOI: |
10.1007/s00423-021-02409-0 |
Popis: |
Repeated hepatectomies in the therapeutic route of patients with colorectal liver metastases (CRLM) may improve their long term survival. Hepatic vein (HV) resection and reconstruction allows parenchyma-sparing hepatectomy (PSH) and R0 resections for CRLM in contact with one HV. We aimed at verifying the feasibility of PSH with double HV resection and direct reconstruction for CRLM in contact with two HVs at the hepatocaval confluence.Out of 106 consecutive PSH performed for CRLM deep-located in segments I-IVa-VII-VIII, four (3.7%) PSH were performed with resection of CRLM en bloc with two adjacent HVs which were both reconstructed with double direct HV anastomosis: 3 cases between right-HV and middle-HV and 1 case between middle-HV and left-HV. Two patients had previously undergone liver resection. Three patients had one single lesion and one had 5 CRLMs.Median size of CRLMs in contact with HVs was 25 mm (range 22-30 mm). At histological examination, all resections were R0 except one R1-vascular (detachment from glissonean pedicle): in all cases at least one HV and in 1 case both HVs were infiltrated by the tumor cells. After median follow-up of 18 (range 3.5-41.2) months, all HVs were patent. All patients were alive and in good general conditions, and 3 patients were disease free (one of them following a liver re-resection). One patient experienced a grade IIIa complication. Median hospital-stay was 11 (range 9-13) days.In patients with CRLMs involving two adjacent HVs at the hepatocaval confluence, liver resection with double HV resection and direct reconstruction is feasible and may be considered to guarantee oncological radicality (R0) and spare health parenchyma. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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