Quality of life in keratoconus: evaluation with Keratoconus Outcomes Research Questionnaire (KORQ)
| Autor: | Ricardo Y. Abe, Flávia Cid Gomes, Arthur Gustavo Fernandes, Paulo Rodolfo Tagliari Barbisan, Alexandre Fattah Martini, Carlos Eduardo Leite Arieta, Daniel Borges, Roberto Damian Pacheco Pinto, Monica Alves |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male Quality of life medicine.medical_specialty Keratoconus Multivariate analysis Visual acuity Adolescent genetic structures Corneal diseases Science Visual Acuity Comorbidity Severity of Illness Index Article law.invention Young Adult 03 medical and health sciences 0302 clinical medicine law Surveys and Questionnaires Bayesian multivariate linear regression Internal medicine Outcome Assessment Health Care medicine Humans Public Health Surveillance 030212 general & internal medicine Eye manifestations Univariate analysis Multidisciplinary Keratometer business.industry Corneal Topography Middle Aged medicine.disease eye diseases 030221 ophthalmology & optometry Medicine Female sense organs Symptom Assessment Outcomes research medicine.symptom business |
| Zdroj: | Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021) Scientific Reports |
| ISSN: | 2045-2322 |
| Popis: | To assess the quality of life of keratoconus patients using the Keratoconus Outcomes Research Questionnaire (KORQ), translated and validated in Portuguese language. The KORQ is the only validated keratoconus specific questionnaire and has a high rating for its psychometric properties. This cross-sectional study enrolled 100 keratoconus patients from a tertiary referral eye hospital between April 2018 and June 2019. Associations between age, sex, allergic conjunctivitis, keratoconus stage, best-corrected visual acuity (BCVA), maximum simulated keratometry (Kmax), steep keratometry (K2), pachymetry, treatments performed, hydrops, and KORQ scores were evaluated using univariate (Wilcoxon test and the Kruskal Wallis test) and multivariate linear regression with stepwise backward modeling. Lower KORQ scores are associated with better quality of life, whereas, higher scores are associated with greater impairment of functional activities and symptoms. Among the 100 patients, mild, moderate, and severe keratoconus were observed in 15%, 46% and 39% of participants, respectively. Univariate analysis showed lower function scores values, with male sex (p p p p = 0.022), while symptom scores were only significantly associated with only BCVA p |
| Databáze: | OpenAIRE |
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