Enhanced Accuracy of Optical Platelet Counts in Microcytic Anemia
| Autor: | Ching-Mei Chen, Cheuk-Kwan Sun, Lin-Lin Pan, Wan-Ting Huang |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Sysmex XE-2100 medicine.diagnostic_test Platelet Count business.industry Microcytic anemia Biochemistry (medical) Clinical Biochemistry Anemia Normal mcv medicine.disease Gastroenterology Case-Control Studies Internal medicine Platelet counting Immunology Automated analyzer Humans Medicine Platelet In patient business Mean corpuscular volume |
| Zdroj: | Laboratory Medicine. 45:32-36 |
| ISSN: | 1943-7730 0007-5027 |
| DOI: | 10.1309/lm7qpuldm5ihbo3l |
| Popis: | Objective: To determine whether microcytic erythrocytes influence the accuracy of automated platelet (PLT) counting. Methods: We divided a total of 206 K 2 ethylenediaminetetraacetic acid (EDTA)–anticoagulated blood samples into 4 groups, as follows: In group 1 (control group), normal mean corpuscular volume (MCV > 80 fL) and PLT count equal or greater than 140,000/μL (n = 45); group 2, normal MCV, reduced PLT count (< 140 x 10 3 /μL, n = 41); group 3, microcytic samples with normal PLT count (n = 68); and group 4, microcytic samples with reduced PLT count (n = 49). We also compared the platelet counting using electroimpedance (PLT-EI), platelet count using fluorescent optical (PLT-FO), and platelet-count manual (PLT-M) methods, using the Sysmex XE 2100 automatic analyzer. Results: Despite highly significant overall correlations between PLT-EI and PLT-FO, PLT-EI and PLT-M, and PLT-FO and PLT-M (r = 0.95 [all P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|