Exposure to maternal depressive symptoms in childhood and adolescent suicide-related thoughts and attempts: mediation by child psychiatric symptoms
| Autor: | Susan J. Bondy, Anne E. Rhodes, Rinku Sutradhar, Sarah M. Goodday, Hilary K. Brown |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Epidemiology Poison control Suicide Attempted child psychiatry Adolescents Suicide prevention Cohort Studies 0302 clinical medicine Child of Impaired Parents Risk Factors Child and adolescent psychiatry Longitudinal Studies Child education.field_of_study 05 social sciences Psychiatry and Mental health Child Preschool Female prospective study 050104 developmental & child psychology Cohort study Adult Canada medicine.medical_specialty Adolescent National Longitudinal Survey of Children and Youth Offspring Population Mothers Suicidal Ideation Young Adult 03 medical and health sciences Injury prevention medicine Humans mediation 0501 psychology and cognitive sciences education Psychiatry suicide Depressive Disorder business.industry Public Health Environmental and Occupational Health Infant Original Articles 030227 psychiatry Adolescent Behavior Attention Deficit Disorder with Hyperactivity business |
| Zdroj: | Epidemiology and Psychiatric Sciences |
| ISSN: | 2045-7979 2045-7960 |
| DOI: | 10.1017/s2045796018000847 |
| Popis: | Aims The nature of the association between child psychiatric symptoms and adolescent suicide-related thoughts (SRT) and attempts (SA) remains unclear. Our objective was to assess whether child psychiatric symptoms from 6 to 10 years of age mediate the association between exposure to maternal depressive symptoms in childhood and offspring SRT and SA in adolescence. Methods A population-based cohort study was constructed by linking all eight cycles from the National Longitudinal Survey of Children and Youth (NLSCY), a nationally representative Canadian panel survey conducted from 1994 to 2009. Self-reported maternal depressive symptoms were measured when offspring were between 0 and 5 years. Maternal-reported child psychiatric symptoms and psychiatric comorbid symptoms were measured from 6 to 10 years, and offspring self-reported SRT and SA were measured between 11 and 19 years. Indirect effects, the effect proportion mediated and their corresponding bootstrapped 95% confidence intervals (CI) were estimated. Results Hyperactivity and inattention significantly mediated the association between maternal depressive symptoms in childhood and risk of both SRT and SA from 11 to 19 years, where approximately 60% (SRT 95% CI 23–94%; SA 95% CI 27–95%) of this association was explained by hyperactivity and inattention. Psychiatric comorbid symptoms also significantly mediated this relationship and accounted for 50% (95% CI 18–81%) of this association with SA. Conclusions Targeting hyperactivity and inattention, and co-occurring psychiatric symptoms in offspring of depressed mothers could reduce risk of SRT, eventual SA and halt progression towards suicide. However, further understanding of comorbid psychiatric symptoms in childhood that most strongly predict adolescent SA is needed. |
| Databáze: | OpenAIRE |
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