Termiglaucescin, a new polyhydroxy triterpene glucoside fromTerminalia glaucescenswith antioxidant and anti-inflammatory potential
| Autor: | Emmanuel Talla, Kauser Siddiqui, Muhammad Ali Shaiq, Bonabenture Tchaleu Ngadjui, Gilbert D W F Kapche, Benjamin Tangue Talom, Fawai Yakai, Amadou Dawe, Iqbal Lubna |
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| Rok vydání: | 2016 |
| Předmět: |
Protein Denaturation
Erythrocytes Magnetic Resonance Spectroscopy Antioxidant medicine.drug_class medicine.medical_treatment Anti-Inflammatory Agents Ethyl acetate Hemolysis 01 natural sciences Antioxidants General Biochemistry Genetics and Molecular Biology Anti-inflammatory Structure-Activity Relationship chemistry.chemical_compound Glucosides Picrates Glucoside Triterpene Botany medicine Humans Lipoxygenase Inhibitors chemistry.chemical_classification Plants Medicinal Stigmasterol Combretaceae Molecular Structure biology Traditional medicine Plant Extracts 010405 organic chemistry Chemistry Biphenyl Compounds Serum Albumin Bovine Saponins biology.organism_classification Triterpenes 0104 chemical sciences 010404 medicinal & biomolecular chemistry visual_art Terminalia visual_art.visual_art_medium Bark Phytotherapy |
| Zdroj: | Zeitschrift für Naturforschung C. 72:203-208 |
| ISSN: | 1865-7125 0939-5075 |
| DOI: | 10.1515/znc-2016-0178 |
| Popis: | Termiglaucescin (1), a new triterpene glucoside, has been isolated from the ethyl acetate extract of the root bark ofTerminalia glaucescensPlanch. ex Benth, together with 11 known compounds,β-D-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (2), arjunglucoside I (3), sericoside (4), arjungenin (5), sericic acid (6), arjunetin (7), chebuloside II (8), 3,3′,4-tri-O-methylelagic acid (9), 3,3′-di-O-methylelagic acid (10),β-sitosterol (11) and stigmasterol (12). Compounds2,3,7,8and9are reported from the plant for the first time. The structures of the isolated compounds were characterized by spectroscopic data interpretations, especially 1D and 2D NMR. The triterpenic isolates showed potent antioxidant and anti-inflammatory activities. |
| Databáze: | OpenAIRE |
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