Termiglaucescin, a new polyhydroxy triterpene glucoside fromTerminalia glaucescenswith antioxidant and anti-inflammatory potential

Autor: Emmanuel Talla, Kauser Siddiqui, Muhammad Ali Shaiq, Bonabenture Tchaleu Ngadjui, Gilbert D W F Kapche, Benjamin Tangue Talom, Fawai Yakai, Amadou Dawe, Iqbal Lubna
Rok vydání: 2016
Předmět:
Protein Denaturation
Erythrocytes
Magnetic Resonance Spectroscopy
Antioxidant
medicine.drug_class
medicine.medical_treatment
Anti-Inflammatory Agents
Ethyl acetate
Hemolysis
01 natural sciences
Antioxidants
General Biochemistry
Genetics and Molecular Biology
Anti-inflammatory
Structure-Activity Relationship
chemistry.chemical_compound
Glucosides
Picrates
Glucoside
Triterpene
Botany
medicine
Humans
Lipoxygenase Inhibitors
chemistry.chemical_classification
Plants
Medicinal
Stigmasterol
Combretaceae
Molecular Structure
biology
Traditional medicine
Plant Extracts
010405 organic chemistry
Chemistry
Biphenyl Compounds
Serum Albumin
Bovine
Saponins
biology.organism_classification
Triterpenes
0104 chemical sciences
010404 medicinal & biomolecular chemistry
visual_art
Terminalia
visual_art.visual_art_medium
Bark
Phytotherapy
Zdroj: Zeitschrift für Naturforschung C. 72:203-208
ISSN: 1865-7125
0939-5075
Popis: Termiglaucescin (1), a new triterpene glucoside, has been isolated from the ethyl acetate extract of the root bark ofTerminalia glaucescensPlanch. ex Benth, together with 11 known compounds,β-D-glucopyranosyl 2α,3β,6β-trihydroxy-23-galloylolean-12-en-28-oate (2), arjunglucoside I (3), sericoside (4), arjungenin (5), sericic acid (6), arjunetin (7), chebuloside II (8), 3,3′,4-tri-O-methylelagic acid (9), 3,3′-di-O-methylelagic acid (10),β-sitosterol (11) and stigmasterol (12). Compounds2,3,7,8and9are reported from the plant for the first time. The structures of the isolated compounds were characterized by spectroscopic data interpretations, especially 1D and 2D NMR. The triterpenic isolates showed potent antioxidant and anti-inflammatory activities.
Databáze: OpenAIRE
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