Incident dementia and faster rates of cognitive decline are associated with worse multisensory function summary scores
| Autor: | Willa D. Brenowitz, Kristine Yaffe, Allison R. Kaup |
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| Rok vydání: | 2020 |
| Předmět: |
Male
cognition Aging Epidemiology Audiology Neurodegenerative Alzheimer's Disease 0302 clinical medicine 030212 general & internal medicine Cognitive decline Health Policy Incidence sensory impairment Rehabilitation Regression analysis Cognition Cognitive test Psychiatry and Mental health Quartile Sensation Disorders Neurological Female epidemiology medicine.medical_specialty Clinical Sciences Article 03 medical and health sciences Cellular and Molecular Neuroscience Developmental Neuroscience Clinical Research Behavioral and Social Science medicine Acquired Cognitive Impairment Dementia Humans Cognitive Dysfunction Aged business.industry Neurosciences Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD) medicine.disease Confidence interval Brain Disorders multisensory Geriatrics Neurology (clinical) Geriatrics and Gerontology business 030217 neurology & neurosurgery |
| Zdroj: | Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 16, iss 10 Alzheimers Dement |
| Popis: | IntroductionWe created a summary score for multiple sensory (multisensory) impairment and evaluated its association with dementia.MethodsWe studied 1794 adults aged 70 to 79 who were dementia-free at enrollment and followed for up to 10 years in the Health, Aging, and Body Composition Study. The multisensory function score (0 to 12 points) was based on sample quartiles of objectively measured vision, hearing, smell, and touch summed overall. Risk of incident dementia and cognitive decline (measured by two cognitive tests) associated with the score were assessed in regression models adjusting for demographics and health conditions.ResultsDementia risk was 2.05 times higher (95% confidence interval [CI] 1.50-2.81) comparing "poor" to "good" multisensory score tertiles and 1.45 times higher comparing the "middle" to "good" tertiles (95% CI 1.09-1.91). Each point worse in the multisensory function score was associated with faster rates of cognitive decline (P |
| Databáze: | OpenAIRE |
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