Adult T-cell leukemia/lymphoma: report of two cases
| Autor: | Helio Moraes-Souza, Sheila Soares, Fabrício Frederico Mendes Martins, Ricardo Aparecido Olivo |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male Microbiology (medical) Pathology medicine.medical_specialty Hepatosplenomegaly Disease Adult T-cell leukemia/lymphoma Fatal Outcome hemic and lymphatic diseases Antineoplastic Combined Chemotherapy Protocols medicine Humans Leukemia-Lymphoma Adult T-Cell Leukocytosis Flower cell biology business.industry Abdominal distension medicine.disease Lymphoma Leukemia Treatment Outcome Infectious Diseases biology.protein Female Parasitology medicine.symptom Antibody business Human T-cell lymphotrophic virus |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical v.41 n.3 2008 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
| ISSN: | 0037-8682 |
| Popis: | Adult T-cell leukemia/lymphoma is a lymphoproliferative disorder of mature T lymphocytes associated with infection with human T-cell lymphotrophic virus type I (HTLV-I). Adult T-cell leukemia/lymphoma is characterized by clinical and laboratory polymorphism that allows it to be classified into four distinct subgroups: smoldering, chronic, acute and lymphomatous types. We present here two cases of adult T-cell leukemia/lymphoma, respectively in the acute and lymphomatous forms of the disease. Case 1 was a 35-year-old woman who presented abdominal distension accompanied by hepatosplenomegaly, adenomegaly, skin lesions, positivity for anti-HTLV-I antibodies and leukocytosis with the presence of flower cells. Case 2 was a 38-year-old man who was admitted with generalized lymphadenomegaly, positivity for anti-HTLV-I antibodies, hypercalcemia and osteolytic lesions. In this paper, we correlate the clinical-laboratory findings of these two cases with data in the literature. |
| Databáze: | OpenAIRE |
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