Human immunodeficiency virus type 1 RNA polymerase chain reaction reasonably excludes infection in exposed infants

Autor:	Wally Bitar, Patricia M. Flynn, Katherine M. Knapp, Jorge Lujan-Zilbermann
Rok vydání:	2003
Předmět:	Microbiology (medical) Population HIV Infections Polymerase Chain Reaction Sensitivity and Specificity Virus law.invention chemistry.chemical_compound law RNA polymerase parasitic diseases Medicine Humans education Child Polymerase chain reaction Self-Sustained Sequence Replication education.field_of_study biology business.industry virus diseases RNA Infant biology.organism_classification NASBA Virology Infectious Disease Transmission Vertical Infectious Diseases chemistry Pediatrics Perinatology and Child Health Lentivirus Immunology HIV-1 RNA Viral Viral disease business
Zdroj:	The Pediatric infectious disease journal. 22(1)
ISSN:	0891-3668
Popis:	A nucleic acid sequence-based amplification (NASBA) assay that detects HIV RNA may be helpful in excluding perinatal HIV infection. We reviewed the records of 190 infants born to HIV-infected mothers. The sensitivity and specificity of the NASBA assay were 100% when measured at two time periods in the first 9 months of life. The HIV RNA NASBA assay should be considered a valid diagnostic test in this population.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c2fe817b5651495b499436f3db8426 https://pubmed.ncbi.nlm.nih.gov/12553306 Zobrazit plný text záznamu