Spatial and Temporal Distribution of Mycobacterium tuberculosis Complex Infection in Eurasian Badger (Meles meles) and Cattle in Asturias, Spain

Autor: Ramón A. Juste, José Ángel Armenteros, Beatriz Romero, Manuel Queipo, Cristina Blanco Vázquez, Mercedes Domínguez, Pablo Quirós, Isabel Merediz, Ana Balseiro, Thiago Doria Barral, Lucas Domínguez, Rosa Casais
Přispěvatelé: Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Ministerio de Agricultura, Pesca y Alimentación (España), Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (España), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (Brasil), Balseiro Morales, Ana María [0000-0002-5121-7264], Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Balseiro Morales, Ana María, CSIC - Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), European Regional Development Fund (ERDF/FEDER), Ministerio de Agricultura, Pesca y Alimentación, Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), España., Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Repisalud
Instituto de Salud Carlos III (ISCIII)
Digital.CSIC. Repositorio Institucional del CSIC
instname
E-Prints Complutense. Archivo Institucional de la UCM
Animals
Volume 11
Issue 5
Animals, Vol 11, Iss 1294, p 1294 (2021)
Popis: 14 páginas, 6 figuras.
The present work investigated the prevalence, spatial distribution, and temporal distribution of tuberculosis (TB) in free-ranging Eurasian badgers (Meles meles) and cattle in Asturias (Atlantic Spain) during a 13-year follow-up. The study objective was to assess the role of badgers as a TB reservoir for cattle and other sympatric wild species in the region. Between 2008 and 2020, 673 badgers (98 trapped and 575 killed in road traffic accidents) in Asturias were necropsied, and their tissue samples were cultured for the Mycobacterium tuberculosis complex (MTC) isolation. Serum samples were tested in an in-house indirect P22 ELISA to detect antibodies against the MTC. In parallel, data on MTC isolation and single intradermal tuberculin test results were extracted for cattle that were tested and culled as part of the Spanish National Program for the Eradication of Bovine TB. A total of 27/639 badgers (4.23%) were positive for MTC based on bacterial isolation, while 160/673 badgers (23.77%) were found to be positive with the P22 ELISA. The rate of seropositivity was higher among adult badgers than subadults. Badger TB status was spatially and temporally associated with cattle TB status. Our results cannot determine the direction of possible interspecies transmission, but they are consistent with the idea that the two hosts may exert infection pressure on each other. This study highlights the importance of the wildlife monitoring of infection and disease during epidemiological interventions in order to optimize outcomes.
This work was funded by the Ministerio de Ciencia, Innovación y Universidades (MCIU), the Agencia Estatal de Investigación (AEI) reference project RTI2018-096010-B-C21 (FEDER co-funded), PCTI 2018–2020 (GRUPIN: IDI2018-000237), and FEDER and Ministerio de Agricultura, Pesca y Alimentación. C.B.V. was supported by a grant from the Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA), Spain. Publication costs were covered with funds from RTI2018- 096010-B-C21 (FEDER co-funded). T.D.B. was supported by a fellowship from the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES; process number 88887.511077/2020-00).
Databáze: OpenAIRE
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