Gemcitabine associated retinopathy and nephropathy
| Autor: | Alan T. Sheyman, K. Bailey Freund, Patricia J. Pahk, Kenneth J. Wald |
|---|---|
| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Antimetabolites Antineoplastic medicine.medical_treatment Urology Vision Disorders Physical examination Deoxycytidine Nephropathy Retinal Diseases medicine Humans Retrospective Studies Chemotherapy medicine.diagnostic_test Renal ischemia business.industry General Medicine Middle Aged medicine.disease Fluorescein angiography Chemotherapy regimen Gemcitabine Ophthalmology Kidney Failure Chronic Female business Retinopathy medicine.drug |
| Zdroj: | Retinal casesbrief reports. 8(2) |
| ISSN: | 1937-1578 |
| Popis: | Purpose: To report a case of presumed gemcitabine-induced retinopathy and nephropathy. Methods: Case Report. Retrospective chart review. Results: A 64-year-old woman with a recent diagnosis of metastatic cholangiocarcinoma presented with progressive visual loss and renal failure shortly after the initiation of a chemotherapy regimen which included gemcitabine. Clinical examination and fluorescein angiography showed findings of severe retinal ischemia. Conclusion: Although gemcitabine chemotherapy has been reported to cause a Purtscher-like retinopathy, we propose in our patient a gemcitabine-induced vasculopathy that lead to significant retinal and renal ischemia. |
| Databáze: | OpenAIRE |
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