Association Between Dry Eye and Polycystic Ovary Syndrome: Subclinical Inflammation May Be Part of the Process
| Autor: | Özgür Kan, Mahmut Asfuroglu, Emre Baser, Yonca Asfuroğlu |
|---|---|
| Přispěvatelé: | [Belirlenecek] |
| Rok vydání: | 2020 |
| Předmět: |
Adult
medicine.medical_specialty OSDI Dry eye Body Mass Index Young Adult chemistry.chemical_compound Schirmer Dehydroepiandrosterone sulfate Internal medicine medicine Humans Ocular Surface Disease Index Polycystic ovary syndrome Unexplained infertility Inflammation medicine.diagnostic_test business.industry Hyperandrogenism Complete blood count Luteinizing Hormone Break-up time medicine.disease Polycystic ovary Ophthalmology Endocrinology Postprandial chemistry Dry Eye Syndromes Female business Luteinizing hormone |
| Zdroj: | Eye & Contact Lens: Science & Clinical Practice. 47:27-31 |
| ISSN: | 1542-2321 |
| DOI: | 10.1097/icl.0000000000000716 |
| Popis: | Purpose: To evaluate the changes in tear function in patients with polycystic ovary syndrome (PCOS) and establish whether there is a correlation between hormonal levels, novel hematologic biomarkers, and dry eye parameters. Material and Method: Forty-seven patients with PCOS and 43 age-matched patients with unexplained infertility were included in the control group. Follicle-stimulating hormone, luteinizing hormone, estradiol, thyroid-stimulating hormone, prolactin, dehydroepiandrosterone sulfate (DHEA-S), 17-OH progesterone, fasting and postprandial glucose, fasting insulin, and cholesterol metabolites were evaluated in both groups. In addition, the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio were obtained from a complete blood count. The Ocular Surface Disease Index (OSDI) questionnaire was administered, and all patients underwent tear break-up time (BUT) and Schirmer I tests. Bivariate correlations were investigated using Spearman correlation coefficient analysis. Results: The mean age of the PCOS group and the control group was 27.66 +/- 3.96 years and 29.28 +/- 6.83 years, respectively. Schirmer I test scores and BUT values were significantly lower and OSDI results were significantly higher in the PCOS group (P=0.003, P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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