Impact of meningococcal vaccination with combined serogroups A and C polysaccharide vaccine on carriage of Neisseria meningitidis C

Autor: S. Fernández, J. A. Vázquez, I. Santiago, A. Malvar, L. Arreaza, S. Berrón, X. Hervada
Rok vydání: 2003
Předmět:
Zdroj: Journal of Medical Microbiology. 52:75-77
ISSN: 1473-5644
0022-2615
DOI: 10.1099/jmm.0.04927-0
Popis: Two studies of meningococcal carriage state were carried out in Galicia (Spain) before and after a mass vaccination campaign between December 1996 and January 1997 against Neisseria meningitidis serogroup C with meningococcal serogroups A and C polysaccharide vaccine. The studies covered two areas with different incidence rates of meningococcal disease in 1996 (high and low incidence). Carriage rates of serogroup C showed a decrease in both areas, 47 and 65 % respectively, before and after the vaccination. Results showed a decrease in carrier state in the age groups 10-14- and 15-19-year-olds, but not in the 5-9-year-olds. These results demonstrate the effect of immunization on the reduction of the carriage state.
Databáze: OpenAIRE