Awareness of the risk of developing medication-related osteonecrosis of the jaw among bisphosphonate users

Autor: Mohammad-Awni Al-Kayed, Ahmad El-Ma'aita, Yazan Hassona, Mais Al-Hattab, Noor Da'as, Mohammad A Al-Rabab'ah
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Risk awareness
Adult
Male
medicine.medical_specialty
Medicine (General)
medicine.medical_treatment
Multidisciplinary team
Biochemistry
patient education
Pre-Clinical Research Report
03 medical and health sciences
0302 clinical medicine
R5-920
Medication-related osteonecrosis of the jaw
Medicine
Humans
antiresorptive drugs
Intensive care medicine
bisphosphonates
multidisciplinary team
Aged
Retrospective Studies
Jordan
Bone Density Conservation Agents
Diphosphonates
business.industry
Biochemistry (medical)
Retrospective cohort study
030206 dentistry
Cell Biology
General Medicine
risk awareness
Bisphosphonate
Middle Aged
medicine.disease
Antiresorptive Drugs
030220 oncology & carcinogenesis
Bisphosphonate-Associated Osteonecrosis of the Jaw
Female
business
Osteonecrosis of the jaw
Patient education
Zdroj: The Journal of International Medical Research
Journal of International Medical Research, Vol 48 (2020)
ISSN: 1473-2300
0300-0605
Popis: Objective In this retrospective observational study, we evaluated awareness among patients using bisphosphonates (BPs) regarding the risk of developing medication-related osteonecrosis of the jaw (MRONJ) and whether they received appropriate dental screening and treatment prior to commencing medication. Methods Patients using BPs who attended the endodontics clinic at Jordan University Hospital in 2019 were interviewed using a pre-designed questionnaire. Data were analysed using descriptive statistics and chi-squared tests. Results In total, 110 patients were interviewed (84 women, 26 men; age 40–78 years). A total of 94 patients were using oral BP and 16 received intravenous (IV) BP. We found that only 12.4% of participants were aware about the risk of MRONJ following BP use, and only one third of them has received information from their prescribing physicians. In total, 5% of participants were referred to a dentist for screening prior to initiating BP treatment. Patients receiving IV BP and those with a university-level education had better awareness about the risk of MRONJ than oral BP users and those with a high school education level. Conclusion Patients’ awareness about MRONJ risk was low in our population. Better patient education and collaboration among physicians and dentists are needed prior to starting BP treatment.
Databáze: OpenAIRE
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