Molar–incisor hypomineralization and the association with childhood illnesses and antibiotics in a group of Finnish children
| Autor: | Satu Alaluusua, Eija Salmela, Anneli Ess, Sakari Laisi, Emma Wuollet |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
Pediatrics
medicine.medical_specialty medicine.drug_class Antibiotics Histamine Antagonists Penicillins Logistic regression Communicable Diseases Health data 03 medical and health sciences Chickenpox 0302 clinical medicine stomatognathic system Incisor Independent samples Prevalence medicine Humans 030212 general & internal medicine Child Dental Enamel Respiratory Tract Infections General Dentistry Finland Retrospective Studies business.industry Medical record Confounding Amoxicillin 030206 dentistry General Medicine Molar Incisor Hypomineralization Molar Anti-Bacterial Agents Bronchodilator Agents Gastroenteritis 3. Good health Antitussive Agents Otitis Media medicine.anatomical_structure Urinary Tract Infections Dental Enamel Hypoplasia Macrolides business |
| Zdroj: | Acta Odontologica Scandinavica. 74:416-422 |
| ISSN: | 1502-3850 0001-6357 |
| Popis: | Molar-incisor hypomineralization (MIH) is a developmental enamel defect affecting 1-4 first permanent molars (FPMs) and often also incisors. The aim of this study was to assess whether childhood illnesses or medication are associated with MIH.FPMs and incisors of 287 Finnish children were examined for MIH in line with the criteria of the EAPD. Health data from the first 3 years of life was collected from medical records and the associations with MIH and MIH2 (lesions in at least one FPM and incisor) were assessed using simple and multiple logistic regression analyses.The prevalence of MIH and MIH2 were 11.5% and 6.3%, respectively. During the first 3 years of life, the children with MIH had sought care for infectious illnesses more often than the children without MIH (mean number of visits (SD) 7.9(6.4) vs. 6.0(5.1), p = 0.045, independent samples t-test). After adjustment for confounding factors, children who had received penicillin or macrolides within the first year, or amoxicillin within the first 3 years had a higher risk for MIH (2.61, 4.07 and 2.58 times, adjusted OR, respectively) or MIH2 (3.16 times, aOR for penicillin and amoxicillin) compared to those who had not received that antibiotic. Of the illnesses, children with at least one episode of otitis within the first year had a higher risk for MIH (2.28 times, aOR) than those who had not suffered from otitis.Acute otitis media and the use of certain antibiotics were associated with the elevated risk of MIH/MIH2. |
| Databáze: | OpenAIRE |
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