Simulation of personalised haemodynamics by various mounting positions of a prosthetic valve using computational fluid dynamics
| Autor: | Marius Geller, Werner Pennekamp, Volkmar Nicolas, Markus Bongert |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Aortic valve
Computer science 0206 medical engineering Biomedical Engineering Hemodynamics 02 engineering and technology Inflow Prosthesis Design Rotation 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Orientation (geometry) medicine Humans media_common.cataloged_instance Heart valve European union Aorta media_common Models Cardiovascular Blood flow Coronary Vessels 020601 biomedical engineering medicine.anatomical_structure Aortic Valve Hydrodynamics Stress Mechanical Blood Flow Velocity Biomedical engineering |
| Zdroj: | Biomedical Engineering / Biomedizinische Technik. 64:147-156 |
| ISSN: | 1862-278X 0013-5585 |
| DOI: | 10.1515/bmt-2017-0092 |
| Popis: | Diseases of the cardiovascular system account for nearly 42% of all deaths in the European Union. In Germany, approximately 12,000 patients receive surgical replacement of the aortic valve due to heart valve disease alone each year. A three-dimensional (3D) numerical model based on patient-specific anatomy derived from four-dimensional (4D) magnetic resonance imaging (MRI) data was developed to investigate preoperatively the flow-induced impact of mounting positions of aortic prosthetic valves to select the best orientation for individual patients. Systematic steady-state analysis of blood flow for different rotational mounting positions of the valve is only possible using a virtual patient model. A maximum velocity of 1 m/s was used as an inlet boundary condition, because the opening angle of the valve is at its largest at this velocity. For a comparative serial examination, it is important to define the standardised general requirements to avoid impacts other than the rotated implantation of the prosthetic aortic valve. In this study, a uniform velocity profile at the inlet for the inflow of the aortic valve and the real aortic anatomy were chosen for all simulations. An iterative process, with the weighted parameters flow resistance (1), shear stress (2) and velocity (3), was necessary to determine the best rotated orientation. Blood flow was optimal at a 45° rotation from the standard implantation orientation, which will offer a supply to the coronary arteries. |
| Databáze: | OpenAIRE |
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