What came first, the virus or the egg: Innate immunity during viral coinfections

Autor:	Meagan D. Rippee‐Brooks, Christopher R. Lupfer, Riley N. Marcinczyk
Rok vydání:	2020
Předmět:	0301 basic medicine Secondary infection Immunology Inflammation Disease Biology Virus 03 medical and health sciences 0302 clinical medicine Immune system medicine Immunology and Allergy Humans Pathogen Innate immune system Bacteria Coinfection fungi food and beverages medicine.disease Immunity Innate 030104 developmental biology Virus Diseases Viruses medicine.symptom 030215 immunology
Zdroj:	Immunological reviewsReferences. 297(1)
ISSN:	1600-065X
Popis:	Infections with any pathogen can be severe and present with numerous complications caused by the pathogen or the host immune response to the invading microbe. However, coinfections, also called polymicrobial infections or secondary infections, can further exacerbate disease. Coinfections are more common than is often appreciated. In this review, we focus specifically on coinfections between viruses and other viruses, bacteria, parasites, or fungi. Importantly, innate immune signaling and innate immune cells that facilitate clearance of the initial viral infection can affect host susceptibility to coinfections. Understanding these immune imbalances may facilitate better diagnosis, prevention, and treatment of such coinfections.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a10e6486bf774e597456b7d5498ff8 https://pubmed.ncbi.nlm.nih.gov/32761626 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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