HAART, DOTS and renal disease of patients co-infected with HIV/AIDS and TB in the South West Region of Cameroon
Autor: | Charlotte Wenze Ayima, Patrick Elroy Weledji, Anna Longdoh Njunda, Dickson Shey Nsagha, Elvis Asangbeng Tanue, Odette Dzemo Kibu, Jules Clement Nguedia Assob, Benjamin Thumamo Pokam |
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Jazyk: | angličtina |
Předmět: |
Adult
Male medicine.medical_specialty Efavirenz Nevirapine HAART Renal function HIV Infections Kidney Function Tests Communicable Diseases chemistry.chemical_compound Zidovudine Young Adult Acquired immunodeficiency syndrome (AIDS) Internal medicine Antiretroviral Therapy Highly Active Prevalence Medicine Humans Cameroon Renal Tuberculosis Pulmonary Aged Creatinine Acquired Immunodeficiency Syndrome DOTS business.industry Coinfection Public Health Environmental and Occupational Health Lamivudine virus diseases Middle Aged medicine.disease Surgery Regimen Cross-Sectional Studies Logistic Models TB chemistry HIV/AIDS Female Kidney Diseases business medicine.drug Research Article |
Zdroj: | BMC Public Health BASE-Bielefeld Academic Search Engine |
ISSN: | 1471-2458 |
DOI: | 10.1186/s12889-015-2331-z |
Popis: | Background Tuberculosis is the commonest infection among HIV/AIDS patients. This co-infection constitutes a major death threat in the world. There is paucity of data about renal disease amongst patients on HAART and DOTS therapy in Cameroon. Methods This was a hospital-based cross-sectional study in the Buea, Limbe and Kumba government Hospitals. Spectrophotometric method was used for the quantitative determination of serum creatinine, urea, albumin and total protein levels. Glomerular filtration rate was estimated using the MDRD method. The student’s t test, ANOVA and logistic regression were used to analyse the data. Results Out of 200 participants, 101 (50.5 %) were males. The ages ranged from 21 to 65 years with a mean age of 38.04 ± 10.52 years. Compared to adults on DOTS alone, adults on HAART alone had a significantly higher prevalence of eGFR |
Databáze: | OpenAIRE |
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