HAART, DOTS and renal disease of patients co-infected with HIV/AIDS and TB in the South West Region of Cameroon

Autor: Charlotte Wenze Ayima, Patrick Elroy Weledji, Anna Longdoh Njunda, Dickson Shey Nsagha, Elvis Asangbeng Tanue, Odette Dzemo Kibu, Jules Clement Nguedia Assob, Benjamin Thumamo Pokam
Jazyk: angličtina
Předmět:
Zdroj: BMC Public Health
BASE-Bielefeld Academic Search Engine
ISSN: 1471-2458
DOI: 10.1186/s12889-015-2331-z
Popis: Background Tuberculosis is the commonest infection among HIV/AIDS patients. This co-infection constitutes a major death threat in the world. There is paucity of data about renal disease amongst patients on HAART and DOTS therapy in Cameroon. Methods This was a hospital-based cross-sectional study in the Buea, Limbe and Kumba government Hospitals. Spectrophotometric method was used for the quantitative determination of serum creatinine, urea, albumin and total protein levels. Glomerular filtration rate was estimated using the MDRD method. The student’s t test, ANOVA and logistic regression were used to analyse the data. Results Out of 200 participants, 101 (50.5 %) were males. The ages ranged from 21 to 65 years with a mean age of 38.04 ± 10.52 years. Compared to adults on DOTS alone, adults on HAART alone had a significantly higher prevalence of eGFR
Databáze: OpenAIRE