Prognostic factors for recovery of health status after injury: A prospective multicentre cohort study
| Autor: | Leonie de Munter, Mariska A. C. de Jongh, Suzanne Polinder, Roos J.M. Havermans, Ewout W. Steyerberg |
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| Přispěvatelé: | Public Health |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Visual analogue scale Traumatic brain injury Health Status Population lcsh:Medicine Cohort Studies 03 medical and health sciences 0302 clinical medicine emergency medicine Epidemiology accident & emergency medicine Medicine Humans 030212 general & internal medicine Longitudinal Studies Prospective Studies Trial registration education Netherlands education.field_of_study business.industry lcsh:R 030208 emergency & critical care medicine Cognition General Medicine accident medicine.disease Prognosis Physical therapy Quality of Life trauma management Spine injury epidemiology business Cohort study |
| Zdroj: | BMJ Open, 11(1):e038707. BMJ Publishing Group BMJ Open BMJ Open, 11(1). BMJ PUBLISHING GROUP BMJ Open, Vol 11, Iss 1 (2021) |
| ISSN: | 2044-6055 |
| Popis: | ObjectivesTo determine prognostic factors for health status and recovery patterns during the first 2 years after injury in the clinical trauma population.DesignA prospective longitudinal cohort study.SettingTen participating hospitals in Brabant, the Netherlands.ParticipantsInjured adult patients admitted to a hospital between August 2015 and November 2016 were followed: 4883 (50%) patients participated.Main outcome measuresPrimary outcome was health status, measured with the EuroQol-5-dimensions-3-levels (EQ-5D), including a cognition item and the EuroQol Visual Analogue Scale. Health status was collected at 1 week, 1, 3, 6, 12 and 24 months after injury. Potential prognostic factors were based on literature and clinical experience (eg, age, sex, pre-injury frailty (Groningen Frailty Index), pre-injury EQ-5D).ResultsHealth status increased mainly during the first 6 months after injury with a mean EQ-5D utility score at 1 week of 0.49 and 0.79 at 24 months. The dimensions mobility, pain/discomfort and usual activities improved up to 2 years after injury. Lower pre-injury health status, frailty and longer length of stay at the hospital were important prognostic factors for poor recovery. Spine injury, lower and upper extremity injury showed to be prognostic factors for problems after injury. Traumatic brain injury was a prognostic factor for cognitive problems.ConclusionThis study contributes to the increase in knowledge of health recovery after injury. It could be a starting point to develop prediction models for specific injury classifications and implementation of personalised medicine.Trial registration numberNCT02508675. |
| Databáze: | OpenAIRE |
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