Importance and antimicrobial resistance of 'Mycoplasma bovis' in clinical respiratory disease in feedlot calves
| Autor: | Francisco Rodríguez, Ángel Gómez-Martín, Joaquín Ortega, Christian de la Fe, Ana García-Galán, Ángel García-Muñoz, J. Seva |
|---|---|
| Přispěvatelé: | Producción Científica UCH 2021, UCH. Departamento de Producción y Sanidad Animal, Salud Pública Veterinaria y Ciencia y Tecnología de los Alimentos |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Veterinary medicine
Bovine respiratory disease Bacterias - Resistencia a los medicamentos minimum inhibitory concentration Drug resistance in microorganisms Ganado vacuno - Enfermedades infecciosas Microbiology Micoplasmosis en los animales Antibiotic resistance feedlot calves SF600-1100 Bacteriology pneumonia Medicine antimicrobial resistance Pathogen Cattle - Communicable diseases Antibióticos en veterinaria Bacterial disease General Veterinary business.industry Respiratory disease Antibiotics in veterinary medicine medicine.disease Antimicrobial Pneumonia QL1-991 Veterinary bacteriology Bacteriología veterinaria Animal Science and Zoology business Zoology Mycoplasma diseases in animals Mycoplasma bovis |
| Zdroj: | Animals Volume 11 Issue 5 CEU Repositorio Institucional Fundación Universitaria San Pablo CEU (FUSPCEU) Animals, Vol 11, Iss 1470, p 1470 (2021) |
| DOI: | 10.3390/ani11051470 |
| Popis: | Bovine respiratory disease (BRD) is an important viral and/or bacterial disease that mainly affects feedlot calves. The involvement of Mycoplasma bovis in BRD can lead to chronic pneumonia poorly responsive to antimicrobial treatment. Caseonecrotic bronchopneumonia is a pulmonary lesion typically associated with M. bovis. In Spain, M. bovis is widely distributed in the feedlots and circulating isolates are resistant to most antimicrobials in vitro. However, the role of this species in clinical respiratory disease of feedlot calves remains unknown. Furthermore, available data are relative to a fixed panel of antimicrobials commonly used to treat BRD, but not to the specific set of antimicrobials that have been used for treating each animal. This study examined 23 feedlot calves raised in southeast Spain (2016–2019) with clinical signs of respiratory disease unresponsive to treatment. The presence of M. bovis was investigated through bacteriology (culture and subsequent PCR), histopathology and immunohistochemistry. The pathogen was found in 86.9% (20/23) of the calves, mainly in the lungs (78.26% 18/23). Immunohistochemistry revealed M. bovis antigens in 73.9% (17/23) of the calves in which caseonecrotic bronchopneumonia was the most frequent lesion (16/17). Minimum inhibitory concentration assays confirmed the resistance of a selection of 12 isolates to most of the antimicrobials specifically used for treating the animals in vivo. These results stress the importance of M. bovis in the BRD affecting feedlot calves in Spain. |
| Databáze: | OpenAIRE |
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