Successful treatment with voriconazole of invasive aspergillosis in chronic granulomatous disease
| Autor: | J.L. Yntema, Paul E. Verweij, Jacques F. Meis, Corry M.R. Weemaes, R. van Dalen, L.G.F.M. van 't Hek |
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| Rok vydání: | 1998 |
| Předmět: |
Pulmonary and Respiratory Medicine
Male Antifungal Agents medicine.medical_treatment Filgrastim Pathogenese epidemiologie en behandeling van microbiële infecties Critical Care and Intensive Care Medicine Aspergillosis Granulomatous Disease Chronic Aspergillus nidulans Pathogenesis epidemiology and treatment of microbial infections Chronic granulomatous disease Interferon Amphotericin B Medicine Humans Mycosis Voriconazole Chemotherapy Lung Diseases Fungal business.industry Triazoles medicine.disease Pyrimidines Child Preschool Immunology business medicine.drug |
| Zdroj: | American Journal of Respiratory and Critical Care Medicine, 157, 1694-1696 American Journal of Respiratory and Critical Care Medicine, 157, pp. 1694-1696 |
| ISSN: | 1073-449X |
| Popis: | A 5-year-old boy with chronic granulomatous disease (CGD) was treated with amphotericin B for an invasive pulmonary Aspergillus nidulans infection. The infection progressed during 6 wk of treatment despite the addition of interferon- γ (IFN- γ ), filgrastim, and transfusions with donor granulocytes. Treatment with a novel antifungal triazole, voriconazole, resulted in an excellent clinical response. van ‘t Hek LG, Verweij PE, Weemaes CM, van Dalen R, Yntema J-B, Meis JF. Successful treatment with voriconazole of invasive aspergillosis in chronic granulomatous disease. |
| Databáze: | OpenAIRE |
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