Effect of treatment of calcium kinetics in metabolic bone disease
| Autor: | Joan E. Harrison, E.R. Yendt, T.A. Bayley, K. G. McNeill, A. J. W. Hitchman, Donald Fraser, J. M. Finlay |
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| Rok vydání: | 1971 |
| Předmět: |
Adult
Calcium Isotopes Male Vitamin medicine.medical_specialty Glutens Endocrinology Diabetes and Metabolism Osteoporosis chemistry.chemical_element Rickets Calcium Metabolic bone disease chemistry.chemical_compound Endocrinology Calcium Metabolism Disorders Internal medicine medicine Vitamin D and neurology Humans Vitamin D Aged Demeclocycline Chemistry Methandrostenolone Infant Middle Aged Tetracycline medicine.disease Steatorrhea Kinetics Hydrochlorothiazide Blood chemistry Child Preschool Female Dietary Proteins Bone Diseases medicine.symptom Diet Therapy |
| Zdroj: | Metabolism. 20:1107-1118 |
| ISSN: | 0026-0495 |
| DOI: | 10.1016/0026-0495(71)90035-7 |
| Popis: | The effect of treatment on calcium kinetic and balance studies was investigated on six patients with osteoporosis (group A). The results were compared with data obtained from similar studies on four patients with calcium abnormalities secondary to steatorrhea and on one infant with vitamin D-dependent rickets (group B). The studies were carried out before treatment and subsequently at various periods up to 2 yr after the onset of treatment. The effect of treatment on bone calcium kinetics differed significantly between the two groups. In osteoporosis (group A), accretion rates of calcium to bone were lower as compared to pretreatment values. In contrast, in four of the five subjects of group B, accretion rates increased from pretreatment values. The results show that in osteoporosis changes in bone calcium metabolism were observed for as long as 2 yr on treatment, despite the fact that the balance data were normal at this time. |
| Databáze: | OpenAIRE |
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