Bispectral index in calves anesthetized with xylazine, midazolam, ketamine, isoflurane and subjected to continuous rate infusion of lidocaine
| Autor: | André Moreira Martins Arruda, M. A. Araújo, Verônica Batista de Albuquerque, Lu Shi Cheng, Carolina Aparecida Carlin Beloti, Maurício Deschk, Paulo Sergio Patto dos Santos |
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| Přispěvatelé: | Federal University of Mato Grosso do Sul (UFMS), Universidade Estadual Paulista (Unesp), Universidade Estadual de Campinas (UNICAMP), Galeno Research Unit |
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Male
Xylazine Time Factors Lidocaine Consciousness RD1-811 Midazolam Intermittent Positive-Pressure Ventilation Bolus (medicine) Consciousness Monitors Heart Rate Monitoring Intraoperative medicine Animals Hypnotics and Sedatives Ketamine Anesthesia Arterial Pressure Infusions Intravenous Anesthetics Chromatography Isoflurane business.industry Reproducibility of Results Anesthesia inhalation Bispectral index Anesthesia Recovery Period Premedication Surgery Cattle business medicine.drug |
| Zdroj: | Acta Cirurgica Brasileira, Volume: 30, Issue: 1, Pages: 67-72, Published: JAN 2015 Acta Cirurgica Brasileira, Vol 30, Iss 1, Pp 67-72 (2015) Acta Cirúrgica Brasileira v.30 n.1 2015 Acta Cirúrgica Brasileira Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia (SBDPC) instacron:SBDPC SciELO Repositório Institucional da UNESP Universidade Estadual Paulista (UNESP) instacron:UNESP |
| ISSN: | 0102-8650 |
| Popis: | Made available in DSpace on 2015-08-26T19:19:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-01. Added 1 bitstream(s) on 2015-08-31T13:04:55Z : No. of bitstreams: 1 S0102-86502015000100067.pdf: 282258 bytes, checksum: 1272a5ff25250aa8914c9f358e597b5c (MD5) Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) PURPOSE: To assess the bispectral index (BIS) and recovery in calves anesthetized with xylazine, midazolam, ketamine and isoflurane and subjected to CRI of lidocaine. METHODS: Xilazine was administered followed by ketamine and midazolam, orotracheal intubation and maintenance on isoflurane using mechanical ventilation. Lidocaine (2 mg kg-1 bolus) or saline (0.9%) was administered IV followed by a CRI (100 µg kg-1 minute-1) of lidocaine (L) or saline (C). Were recorded BIS, heart rate (HR), mean arterial pressure (MAP) and rectal temperature (RT) before administration of premedication (TB) and 15 minutes after (TX), before administering lidocaine (T0) and 20, 40, 60 and 80 minutes after the start of the CRI . Time do sternal recumbency (SRE) and standing (ST) and plasma lidocaine concentration also evaluated. RESULTS: In both treatments BIS decreased significantly at all times compared to TB. TX was higher than the subsequent times. HR decreased from baseline at all times and decreased from T40 in L compared to C. SRE was higher in L compared to C. CONCLUSIONS: Bispectral index values were consistent with the degree of hypnosis of the animals. Lidocaine did not potentiate isoflurane anesthesia assessed by BIS in unstimulated calves anesthetized with constant E´Iso. Lidocaine increased the time to sternal recumbency. Federal University of Mato Grosso do Sul Faculty of Veterinary Medicine and Animal Science Sao Paulo State University Faculty of Veterinary Medicine UNESP Faculty of Veterinary Medicine State University of Campinas, Department of Pharmacology Galeno Research Unit UNESP Faculty of Veterinary Medicine Department of Clinical, Surgery and Animal Reproduction Sao Paulo State University, Faculty of Veterinary Medicine Department of Clinical, Surgery and Animal Reproduction FAPESP: 2008/07555-0 FAPESP: 2009/08879-6 |
| Databáze: | OpenAIRE |
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