The Effect of Aging on Anaerobic and Aerobic Enzyme Activities in Human Skeletal Muscle
Autor: | Jan J. Kaczor, Mark A. Tarnopolsky, Wieslaw Ziolkowski, Stanisław Hać, Jerzy Popinigis, Jedrzej Antosiewicz |
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Rok vydání: | 2006 |
Předmět: |
Adult
Male Aging medicine.medical_specialty Adenylate kinase Dehydrogenase chemistry.chemical_compound Oxygen Consumption Internal medicine Lactate dehydrogenase medicine Humans Ketoglutarate Dehydrogenase Complex Carnitine Creatine Kinase Life Style Abdominal Muscles Aged Carnitine O-Palmitoyltransferase L-Lactate Dehydrogenase biology business.industry Adenylate Kinase Skeletal muscle Middle Aged Enzyme assay Endocrinology medicine.anatomical_structure chemistry biology.protein Creatine kinase Geriatrics and Gerontology business Anaerobic exercise medicine.drug |
Zdroj: | The Journals of Gerontology Series A: Biological Sciences and Medical Sciences. 61:339-344 |
ISSN: | 1758-535X 1079-5006 |
Popis: | The effect of aging on metabolic enzyme activity remains controversial, possibly due to physical activity differences. We examined the effect of aging on the enzyme activity for anaerobic and aerobic pathways in nonweight-bearing human skeletal muscle from relatively sedentary males. The muscle obliquus internus abdominis was analyzed for anaerobic (creatine kinase, adenylate kinase, and lactate dehydrogenase) and aerobic (2-oxoglutarate dehydrogenase and carnitine palmitoyltransferase) enzyme activities in two groups: middle-aged (29-54 years) and older (61-74 years) adults. All enzyme activities were lower in older versus middle-aged adults when results were expressed as muscle wet weight (p |
Databáze: | OpenAIRE |
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