Fatal pulmonary fibrosis from low-dose bleomycin therapy
| Autor: | Fairman Rp, Via Ct, Bechard De, DeBlois Gg |
|---|---|
| Rok vydání: | 1987 |
| Předmět: |
Male
medicine.medical_specialty Pulmonary toxicity Pulmonary Fibrosis Bleomycin Gastroenterology Hypoxemia chemistry.chemical_compound Internal medicine Pulmonary fibrosis Antineoplastic Combined Chemotherapy Protocols medicine Humans Cyclophosphamide Aged Lung business.industry Lymphoma Non-Hodgkin Bleomycin Sulfate General Medicine respiratory system medicine.disease respiratory tract diseases Lymphoma carbohydrates (lipids) medicine.anatomical_structure chemistry Doxorubicin Vincristine Toxicity Prednisone medicine.symptom business |
| Zdroj: | Southern medical journal. 80(5) |
| ISSN: | 0038-4348 |
| Popis: | Six weeks after receiving a total dose of 20 units of bleomycin sulfate as part of BACOP therapy for non-Hodgkin's lymphoma, our patient had dyspnea and cough with marked hypoxemia. Open lung biopsy established the diagnosis of "bleomycin lung," confirmed by postmortem examination. Fatal bleomycin pulmonary toxicity can develop with any dosage, and routine tests are incapable of detecting early, reversible toxicity. |
| Databáze: | OpenAIRE |
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