Private specificity of H-2Ldx molecule detected serologically by a surface antigen redistribution method (capping)
| Autor: | Peter Demant, Dagmar Ivanyi |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
medicine.drug_class
T-Lymphocytes Immunology Mice Inbred Strains Monoclonal antibody Biochemistry Epitopes Mice Inbred strain Antigen Genetics medicine Animals Immunology and Allergy Molecule Redistribution (chemistry) Immunologic Capping biology Chemistry Haplotype H-2 Antigens Antibodies Monoclonal General Medicine Molecular biology Antigens Surface biology.protein Antibody |
| Zdroj: | Tissue Antigens. 20:274-281 |
| ISSN: | 0001-2815 |
| DOI: | 10.1111/j.1399-0039.1982.tb00357.x |
| Popis: | The presence of H-2·1 positive-H-2·63 negative molecules, H-2Ldx, in the products of the dx region was originally detected in H-2dx inbred strains GRS/A and LIS/A (Snoek et al. 1979). This study confirms the existence of H-2Ldx molecules in 2 congeneic strains with a H-2dx haplotype on C3H (C3H·LG strain) and B10 (B10·GR strain) background. Besides anti-H-2·1-like antibodies present in anti-Ddx allo-antiserum, monoclonal antibody d anti-k (H100-5/28, H-2·m3) was shown to react with H-2Ldx molecule. Furthermore, evidence is shown that H-2Ldx molecule has a unique specificity, which is detected serologically in a capping experiment. |
| Databáze: | OpenAIRE |
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