Herpes Simplex Encephalitis: Lack of Clinical Benefit of Long-term Valacyclovir Therapy

Autor:	Allen J. Aksamit, Clas Ahlm, Gretchen A. Cloud, Richard J. Whitley, Marie Studahl, Daniel F. Hanley, John W. Gnann, Fred Y. Aoki, Penelope Jester, Salvador Cruz-Flores, Daniel R. Hinthorn, Ilet Dale, Silvia Schliamser, Diane Hanfelt-Goade, Paul D. Griffiths, Elisabeth Aurelius, John Hart, Lil Miedzinski, Britt Marie Eriksson, Alan Jackson, Birgit Sköldenberg
Rok vydání:	2015
Předmět:	Microbiology (medical) Simplexvirus Pediatrics medicine.medical_specialty food.ingredient Adult patients Combination therapy business.industry viruses Antiviral therapy virus diseases medicine.disease medicine.disease_cause Infectious Diseases food Herpes simplex virus Immunology medicine Adverse effect business Articles and Commentaries Encephalitis
Zdroj:	Clinical Infectious Diseases. 61:683-691
ISSN:	1537-6591 1058-4838
DOI:	10.1093/cid/civ369
Popis:	In a multicenter, randomized controlled clinical trial, administration of valacyclovir for 90 days following standard intravenous acyclovir therapy for herpes simplex encephalitis did not improve outcomes, as measured by neuropsychological testing at 12 months.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175841876ff84497ac968aae6b8a9923 https://doi.org/10.1093/cid/civ369 Zobrazit plný text záznamu