Association between alcohol consumption and mammographic density: a hospital-based cross-sectional study
| Autor: | Takahide Okamoto, Akemi Ito |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
Adult medicine.medical_specialty Multivariate analysis Alcohol Drinking Cross-sectional study Logistic regression 03 medical and health sciences Breast cancer screening 0302 clinical medicine Breast cancer Asian People Risk Factors medicine Humans Pharmacology (medical) Radiology Nuclear Medicine and imaging Risk factor Aged Breast Density medicine.diagnostic_test Obstetrics business.industry General Medicine Odds ratio Middle Aged medicine.disease Confidence interval 030104 developmental biology Cross-Sectional Studies Logistic Models Oncology Premenopause 030220 oncology & carcinogenesis Female business |
| Zdroj: | Breast cancer (Tokyo, Japan). 26(4) |
| ISSN: | 1880-4233 |
| Popis: | Mammographic density (MD), the proportion of radiological dense breast, has been reported to be a strong risk factor for breast cancer in many studies. Epidemiological evidence indicates that alcohol consumption increases the risk of breast cancer. In Western countries, a positive association between alcohol consumption and MD has been reported. To investigate the effect of alcohol consumption on MD, we conducted a cross-sectional analysis of healthy women enrolled in a breast cancer screening program at the Ebina Health Service Center, Japan, in 2012, comprising 477 premenopausal women and 308 postmenopausal women. Alcohol consumption was assessed using a self-report questionnaire. Unconditional logistic regression was applied to calculate the odds ratio (OR) and 95% confidence intervals (CI) while adjusting for confounders. The study included 497 women with high breast density (HD group) and 288 women with low breast density (LD group). In all women, multivariate analysis revealed that the OR for HD was significantly increased among women with the highest alcohol intake (≥ 140 g/week of ethanol) compared with abstainers (OR 2.1, 95% CI 1.2–3.9 p = 0.01). The linear trend with increasing alcohol consumption was statistically significant (p = 0.009). MD was positively associated with alcohol consumption in Japanese women. |
| Databáze: | OpenAIRE |
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