Characterization of One-Year Progression of Risk Phenotypes of Diabetic Retinopathy

Autor: Luísa Ribeiro, Inês P. Marques, Rita Coimbra, Torcato Santos, Maria H. Madeira, Ana Rita Santos, Patrícia Barreto, Conceição Lobo, José Cunha-Vaz
Přispěvatelé: Repositório Científico do Instituto Politécnico do Porto
Rok vydání: 2021
Předmět:
Zdroj: Ophthalmology and Therapy
ISSN: 2193-6528
2193-8245
DOI: 10.1007/s40123-021-00437-z
Popis: Introduction We characterized the progression of different diabetic retinopathy (DR) phenotypes in type 2 diabetes (T2D). Methods A prospective longitudinal cohort study (CORDIS, NCT03696810) was conducted with three visits (baseline, 6 months, and 1 year). Demographic and systemic data included age, sex, diabetes duration, lipid profile, and hemoglobin A1c (HbA1c). Ophthalmological examinations included best-corrected visual acuity (BCVA), color fundus photography (CFP), and optical coherence tomography (OCT and OCTA). Phenotype classification was performed at the 6-month visit based on microaneurysm turnover (MAT, on CFP) and central retinal thickness (CRT, on OCT). Only risk phenotypes B (MAT
Databáze: OpenAIRE
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