Late onset of Guillain-Barré syndrome following SARS-CoV-2 infection: part of ‘long COVID-19 syndrome’?
| Autor: | Alice Kane, Mina M Raahimi, Christopher Eg Moore, Ahmad W Alareed |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
Weakness medicine.medical_specialty Neurology Time Factors Neural Conduction Late onset Case Report infectious diseases Guillain-Barre Syndrome Lower motor neuron Late Onset Disorders immunology 03 medical and health sciences 0302 clinical medicine Post-Acute COVID-19 Syndrome medicine Humans Immunologic Factors 030212 general & internal medicine Paresthesia Pneumonitis Muscle Weakness Noninvasive Ventilation Guillain-Barre syndrome business.industry SARS-CoV-2 neurology Electrodiagnosis COVID-19 Immunoglobulins Intravenous Polyradiculoneuropathy General Medicine Middle Aged medicine.disease medicine.anatomical_structure Anesthesia Neuralgia medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | BMJ Case Reports |
| ISSN: | 1757-790X |
| DOI: | 10.1136/bcr-2020-240178 |
| Popis: | We describe a case of delayed onset, acute demyelinating neuropathy secondary to novel SARS-CoV-2 infection. A previously healthy 46-year-old man presented with bilateral leg pain and loss of sensation in his feet 53 days after having COVID-19 pneumonitis. He developed painful sensory symptoms followed by a rapidly progressive lower motor neuron weakness involving all limbs, face and respiratory muscles, needing ventilatory support. In keeping with a diagnosis of Guillain-Barré syndrome, cerebrospinal fluid examination showed albuminocytologic dissociation and nerve conduction studies supported the diagnosis of an acute inflammatory demyelinating polyradiculoneuropathy. The delayed neurological dysfunction seen in our patient following SARS-CoV-2 infection may indicate a novel mechanism of disease that is part of the emerging ‘long COVID-19 syndrome’. |
| Databáze: | OpenAIRE |
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