CLINICAL SIGNS, ANTEMORTEM DIAGNOSTICS, AND PATHOLOGICAL FINDINGS ASSOCIATED WITH MYCOBACTERIUM AVIUM SUBSPECIES PARATUBERCULOSIS INFECTION IN MISHMI TAKIN ( BUDORCAS TAXICOLOR TAXICOLOR)
| Autor: | Douglas Richardson, Simon Girling, Adrian Philbey, Morag Sellar, Jane Harley, Adam D. Naylor |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Pathology medicine.medical_specialty 040301 veterinary sciences Paratuberculosis Enzyme-Linked Immunosorbent Assay Budorcas taxicolor Enteritis Serology Disease Outbreaks 0403 veterinary science medicine Mesenteric lymph nodes Animals General Veterinary biology Mishmi takin 0402 animal and dairy science Outbreak 04 agricultural and veterinary sciences General Medicine Ruminants medicine.disease biology.organism_classification 040201 dairy & animal science Mycobacterium avium subspecies paratuberculosis Mycobacterium avium subsp. paratuberculosis medicine.anatomical_structure Scotland Animal Science and Zoology Animals Zoo Female |
| Zdroj: | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians. 49(2) |
| ISSN: | 1042-7260 |
| Popis: | Mycobacterium avium subspecies paratuberculosis (MAP) is a cause of contagious and typically fatal enteric disease, primarily affecting ruminant and pseudoruminant species. During a MAP outbreak in a captive collection, six of nine adult Mishmi takin ( Budorcas taxicolor taxicolor) showed marked weight loss over 1-3 mo, followed by an acute deterioration. Fecal culture and microscopy failed to identify MAP shedding. Necropsy findings included grossly normal intestines and marked enlargement of mesenteric lymph nodes. Histological findings included multibacillary granulomatous enteritis, mesenteric lymphadenitis, and periportal hepatitis. MAP was confirmed by culture of intestinal and lymph node tissues from the index case. Results of antemortem serological testing using an indirect ELISA (ID SCREEN® Paratuberculosis Indirect) were corroborated by findings at necropsy or survival of the outbreak. Mishmi takin appear to show high MAP susceptibility and a rapid disease course compared with domestic ruminant species. |
| Databáze: | OpenAIRE |
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