Avascular necrosis of the femoral head: An exceptional complication of cushing's disease

Autor:	Hanan El Ouahabi, N. Belmahi, Saïd Boujraf, Maazou Mahamane Larwanou
Rok vydání:	2018
Předmět:	medicine.medical_specialty Avasculaire Case Report 030209 endocrinology & metabolism Avascular necrosis hypercortisolism endogène 03 medical and health sciences Femoral head 0302 clinical medicine Pituitary adenoma medicine 030222 orthopedics medicine.diagnostic_test business.industry Magnetic resonance imaging General Medicine Cushing's disease medicine.disease nécroses Cushing Disease Surgery endogenous hypercortisolism medicine.anatomical_structure Etiology Maladie de Cushing Complication business
Zdroj:	Annals of African Medicine
ISSN:	1596-3519
DOI:	10.4103/aam.aam_75_17
Popis:	Avascular necrosis (AVN) of the femoral head is a well-recognized complication of steroid treatment. Exogenous glucocorticoids’ administration and alcoholism are the most common nontraumatic etiologies. AVN secondary to endogenous hypercortisolism (HC) is rare; very few case reports are available on this complication. We describe a 28-year-old female that has presented an AVN with Cushing's syndrome. Biochemical investigations confirmed HC. Magnetic resonance imaging (MRI) showed a pituitary adenoma that was resected transsphenoidally. The postoperative failure directed to radiosurgery treatment. Then, the patient then expressed a significant clinical improvement while developing adrenocorticotropic deficiency; hence, steroids were indicated. During the discovery of Cushing disease, the patient presented also limping and progressive pain in right hip. The pelvis MRI showed an AVN of the right femoral head. The patient underwent a total replacement of the right hip sine presenting an extensive AVN. This case elucidates that AVN could be an early manifestation of Cushing's disease.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17451f5b9ff617964dd5a9a66a3b30b4 https://doi.org/10.4103/aam.aam_75_17 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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