Cyclic motor activity of the gallbladder maintained in a pylorus-preserving gastrectomy in dogs
| Autor: | Kazuhide Ura, Akihito Enjoji, Kazuyuki Ozeki, Yoshito Ikematsu, Takashi Kanematsu, Mikio Tsukamoto |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Male
Periodicity medicine.medical_specialty medicine.medical_treatment Motor Activity digestive system Gastroenterology Remnant stomach Sincalide Dogs Gastrectomy Internal medicine Animals Medicine Motor activity Antrum Motilin Pylorus Gastrointestinal tract business.industry Gallbladder Stomach digestive oral and skin physiology Pylorus preserving gastrectomy General Medicine digestive system diseases medicine.anatomical_structure Female Surgery sense organs business Muscle Contraction |
| Zdroj: | Surgery Today. 26:489-495 |
| ISSN: | 1436-2813 0941-1291 |
| Popis: | The gallbladder has cyclic motor activity (CMA), which is impaired after a conventional gastrectomy. We conducted experiments to determine whether or not a pylorus-preserving gastrectomy (PPG) could maintain gallbladder CMA. Six strain gauge force transducers were implanted into the gastrointestinal tract and gallbladder of six dogs, respectively. The motor activity of the gastrointestinal tract and gallbladder was recorded as a control. PPG was then carried out. The phasic contractions of the gallbladder, which were correlated with the antral contractions in the control state, were synchronized with contractions of the pylorus after PPG. Intravenous administration of CCK-OP (40 ng/kg) induced phasic contractions of the gallbladder at 4.6 +/- 0.2 c/min in 3 of the 6 days with gastric contractions. After PPG, the gallbladder had phasic contractions (4.5 +/- 0.2 c/m), which were synchronized with the contractions of the pylorus in all dogs regardless of the contractions in the remnant stomach. These findings suggest that gallbladder CMa has a closer relationship with the CMA of the pylorus than with the remnant stomach after PPG. Thus, a preservation of the pylorus at the time of gastric surgery will help in maintaining gallbladder function and coordination with the remnant stomach. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink