Clinical characteristics of functional (psychogenic nonepileptic) seizures: An international retrospective study
| Autor: | Coraline Hingray, Taoufik Alsaadi, David Gigineishvili, Hassan Hosny, Francesco Brigo, Ali A. Asadi-Pooya, Nicholas J. Janocko, Ioannis Karakis, Boulenouar Mesraoua, Alexis Tarrada, Musab Ali, Lubna Elsheikh |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Cross-Cultural Comparison Male Pediatrics medicine.medical_specialty Internationality Adolescent Aura Ethnic group Electroencephalography 03 medical and health sciences Behavioral Neuroscience Epilepsy Young Adult 0302 clinical medicine Seizures Medicine Psychogenic disease Humans Ictal 030212 general & internal medicine Medical History Taking Aged Retrospective Studies medicine.diagnostic_test business.industry Retrospective cohort study Semiology Middle Aged medicine.disease Psychophysiologic Disorders Hospitalization Cross-Sectional Studies Neurology Female Neurology (clinical) business 030217 neurology & neurosurgery |
| Zdroj: | Epilepsybehavior : EB. 111 |
| ISSN: | 1525-5069 |
| Popis: | Purpose We conducted a multicenter international cross-cultural comparative study to investigate clinical semiology and predisposing factors of functional seizures in a large cohort of patients living in different countries around the world. We hypothesized that semiology and predisposing factors of functional seizures differ between various world regions. Methods We conducted this retrospective observational study in adults with functional seizures admitted to epilepsy centers in Iran, Qatar, USA, France, Georgia, Egypt, and United Arab Emirates (UAE). We assessed and compared the demographic and clinical seizure characteristics of these patients, according to the patients' reports and review of the ictal recordings during video-electroencephalogram (EEG) monitoring. Results Five hundred nine patients were included (270 from Iran, 74 from Qatar, 63 from France, 43 from the USA, 22 from Egypt, 20 from UAE, and 17 from Georgia). Although all major manifestations of functional seizures (e.g., aura, loss of responsiveness, generalized motor seizures, ictal injury) were seen in all world regions, seizure semiology differed significantly across countries. Auras, ictal urinary incontinence, and ictal injury were more commonly reported by the American patients than patients from other world regions, whereas loss of responsiveness and generalized motor seizures were more frequently observed in the Iranian and American patients than the European and Arab patients. Conclusion Semiology of functional seizures seems to vary across various regions of the world; socioeconomic, cultural, ethnic, and religious differences may play an essential role in the modulation of functional seizures semiology across different nations and cultures. |
| Databáze: | OpenAIRE |
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