Randomized Controlled Trial of Cognitive-Behavioral and Mindfulness-Based Stress Reduction on the Quality of Life of Patients With Crohn Disease
| Autor: | Michael Friger, Iris Dotan, Shomron Ben Horin, Ganit Goren, Shmuel Odes, Shirley Regev, Doron Schwartz, Anna Nemirovsky, Alon Monsonego, Heba Abu-Kaf, Hagar Banai, Vered Slonim-Nevo, Dan Greenberg, Rami Eliakim, Orly Sarid, Henit Yanai, Livnat Lerner, Ruslan Sergienko, Karny Ilan |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty Mindfulness Psychological intervention Inflammatory bowel disease law.invention Mindfulness-based stress reduction 03 medical and health sciences Cognition 0302 clinical medicine Crohn Disease Randomized controlled trial Quality of life law medicine Humans Immunology and Allergy Depression (differential diagnoses) Depression business.industry Gastroenterology medicine.disease 030220 oncology & carcinogenesis Quality of Life Physical therapy Female 030211 gastroenterology & hepatology business Somatization Stress Psychological |
| Zdroj: | Inflammatory Bowel Diseases. 28:393-408 |
| ISSN: | 1536-4844 1078-0998 |
| DOI: | 10.1093/ibd/izab083 |
| Popis: | Background Patients with Crohn disease have debilitating psychological symptoms, mental fatigue, and poor quality of life. Psychological intervention may improve these symptoms. Methods We performed a randomized parallel-group physician-blinded trial of cognitive-behavioral and mindfulness-based stress reduction (COBMINDEX) on quality of life and psychological symptoms in adults with mild-moderate Crohn disease. COBMINDEX was taught by social workers in one-on-one video conferences over 3 months; quotidian home practice was mandated. Results Fifty-five COBMINDEX and 61 waitlist control patients completed the study; mean age was 33 years and 65% of participants were women. At 3 months, COBMINDEX patients had significantly reduced disease activity (per Harvey-Bradshaw Index score, C-reactive protein level, and calprotectin level), increased quality of life (Short Inflammatory Bowel Disease Questionnaire [SIBDQ] score increased from baseline 41 to 50; P P Conclusions COBMINDEX was effective in increasing patients’ quality of life and reducing psychological symptoms and fatigue. Patients with severe baseline psychological symptoms benefited the most from COBMINDEX. |
| Databáze: | OpenAIRE |
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