Identification of a distinct association fiber tract 'IPS-FG' to connect the intraparietal sulcus areas and fusiform gyrus by white matter dissection and tractography
| Autor: | Atsushi Yamaguchi, Tatsuya Jitsuishi |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
genetic structures Posterior parietal cortex lcsh:Medicine Superior parietal lobule Intraparietal sulcus Biology Article 03 medical and health sciences 0302 clinical medicine Parietal Lobe Neural Pathways Connectome Humans Vertical occipital fasciculus lcsh:Science Aged Aged 80 and over Temporal cortex Multidisciplinary Fusiform gyrus Dissection lcsh:R Middle Aged White Matter Temporal Lobe Diffusion Tensor Imaging 030104 developmental biology lcsh:Q Anatomy Neuroscience 030217 neurology & neurosurgery Tractography |
| Zdroj: | Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020) Scientific Reports |
| ISSN: | 2045-2322 |
| DOI: | 10.1038/s41598-020-72471-z |
| Popis: | The intraparietal sulcus (IPS) in the posterior parietal cortex (PPC) is well-known as an interface for sensorimotor integration in visually guided actions. However, our understanding of the human neural network between the IPS and the cortical visual areas has been devoid of anatomical specificity. We here identified a distinctive association fiber tract “IPS-FG” to connect the IPS areas and the fusiform gyrus (FG), a high-level visual region, by white matter dissection and tractography. The major fiber bundles of this tract appeared to arise from the medial bank of IPS, in the superior parietal lobule (SPL), and project to the FG on the ventral temporal cortex (VTC) in post-mortem brains. This tract courses vertically at the temporo-parieto-occipital (TPO) junction where several fiber tracts intersect to connect the dorsal-to-ventral cortical regions, including the vertical occipital fasciculus (VOF). We then analyzed the structural connectivity of this tract with diffusion-MRI (magnetic resonance imaging) tractography. The quantitative tractography analysis revealed the major streamlines of IPS-FG interconnect the posterior IPS areas (e.g., IP1, IPS1) with FG (e.g., TF, FFC, VVC, PHA2, PIT) on the Human Connectome Project multimodal parcellation atlas (HCP MMP 1.0). Since the fronto-parietal network, including the posterior IPS areas, is recruited by multiple cognitive demands, the IPS-FG could play a role in the visuomotor integration as well as the top-down modulation of various cognitive functions reciprocally. |
| Databáze: | OpenAIRE |
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