Effect of Heparin and Sulfated Polysaccharides on in vitro Hepatic Phagocytosis
| Autor: | James P. Filkins, N. R. Di Luzio |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Male
Phagocytosis In Vitro Techniques Biology General Biochemistry Genetics and Molecular Biology medicine Animals Serum Albumin Radio-Iodinated Mononuclear Phagocyte System Glycosaminoglycans Oxalates Heparin Zymosan Anticoagulants Dextrans Human serum albumin In vitro Rats Gold Colloid Radioactive Liver Biochemistry Rat liver Sulfated polysaccharides Chondroitin medicine.drug |
| Zdroj: | Experimental Biology and Medicine. 122:548-551 |
| ISSN: | 1535-3699 1535-3702 |
| DOI: | 10.3181/00379727-122-31187 |
| Popis: | SummaryColloidal gold phagocytosis by rat liver slices was slight in oxalated rat plasma or serum; however, heparin addition markedly increased the uptake. Heparin also augmented the hepatic phagocytosis of human serum albumin aggregates from oxalated plasma. Other sulfated polysaccharides either had no effect, or only slightly enhanced, gold uptake. The mechanism of heparin action in promoting phagocytosis may be related to facilitation of opsonin-particle interaction. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|