Molecular epidemiological analysis of bat rabies viruses in Brazil
| Autor: | Yuki Kobayashi, Takeo Sakai, Youko Shoji, Tetsuo Sato, Darci Lara Perecin Nociti, Takuya Itou, Fumio Honma Ito, Adolorata Aparecida Bianco Carvalho, Samir Issa Samara, Elenice Maria Sequetin Cunha, Go Sato |
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| Rok vydání: | 2005 |
| Předmět: |
Rabies
Lineage (evolution) Molecular Sequence Data Zoology medicine.disease_cause Species Specificity Chiroptera medicine Animals Cluster Analysis Eptesicus Artibeus Phylogeny DNA Primers General Veterinary biology Molecular epidemiology Base Sequence Geography Reverse Transcriptase Polymerase Chain Reaction Rabies virus Sequence Analysis DNA biology.organism_classification medicine.disease RAIVA Virology Nucleoproteins Nyctinomops Desmodus rotundus Brazil |
| Zdroj: | Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual) Universidade de São Paulo (USP) instacron:USP |
| ISSN: | 0916-7250 |
| Popis: | A molecular epidemiological analysis was performed in 19 rabies viruses (RVs) isolated from haematophagous, frugivorous and insectivorous bats, in Sao Paulo, Brazil. The authors carried out RT-PCR for amplification of the RV nucleoprotein (N) gene, and determined 1,335 nucleotide sequences of N gene by direct sequencing method. Phylogenetic analysis, which was based on the N gene of Brazilian RV isolates identified presently and previously, revealed that RVs isolated from bats were genetically divided into four lineages had a tendency to depend on the host bat species. The first lineage consisted mainly of haematophagous bat (Desmodus rotundus) isolates, including frugivorous bat (Artibeus spp.) isolates. Other three lineages consisted of insectivorous bat isolates; mainly Eptesicus spp., Molossus spp. and Nyctinomops spp. isolates, respectively. These results indicate a possibility of that there are bat species-specific RV variants in Brazil. |
| Databáze: | OpenAIRE |
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