Greater emotional distress is associated with accelerated CD4+ cell decline in HIV infection
| Autor: | E. L. C. Ong, Douglas K. Palmer, Kavita Vedhara, K.H. Nott, E. A. F. Davidson, C. Bradbeer, A.T. Nayagam, M. H. Snow |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Health Status Developmental psychology Life Change Events Acquired immunodeficiency syndrome (AIDS) Immunopathology HIV Seropositivity medicine Humans Longitudinal Studies Homosexuality Male Sida Depression (differential diagnoses) Aged biology Mood Disorders business.industry Middle Aged Stepwise regression medicine.disease biology.organism_classification CD4 Lymphocyte Count Psychiatry and Mental health Clinical Psychology Anxiety Viral disease medicine.symptom business Psychosocial Follow-Up Studies Clinical psychology |
| Zdroj: | Journal of Psychosomatic Research. 42:379-390 |
| ISSN: | 0022-3999 |
| DOI: | 10.1016/s0022-3999(96)00351-0 |
| Popis: | An investigation was conducted to explore the relationship between emotional distress and HIV progression. One hundred twenty-five homosexual, HIV-positive males participated in a 12-month longitudinal investigation. Psychosocial data were collected at 6-month intervals and CD4+ data were collected from diagnosis to the end of the investigation. Principal component analyses were performed initially to identify factors of emotional distress and health status. In addition, CD4+ reliability assessments were performed to ensure the validity of the prognostic assessments made. As a result of these analyses, 47 individuals were eligible for the main analyses. The results from a stepwise regression revealed that disease progression was significantly predicted by CD4+ count at diagnosis (32% of variance) and emotional distress (17% of variance), but was unrelated to subjective perceptions of health. The data suggest that some of the variability in HIV progression can be attributed to emotional distress. |
| Databáze: | OpenAIRE |
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