Exogenous lipoid pneumonia in children: A systematic review
| Autor: | Diana Marangu, Marco Zampoli, Diane Gray, Aneesa Vanker |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
GOR
gastro-oesophageal reflux Biopsy Culture Treatment outcome Mouthwashes Mycobacterium abscessus Global Health Bronchoalveolar Lavage 0302 clinical medicine Adrenal Cortex Hormones Risk Factors 030212 general & internal medicine Child Hypoxia Tachypnea medicine.diagnostic_test biology Palliative Care Oil Treatment efficacy CT computed tomography Anti-Bacterial Agents Pneumonia Lipid Children’s interstitial lung disease (chILD) Laxatives Mycobacterium fortuitum BAL bronchoalveolar lavage Exogenous lipoid pneumonia ORO Oil-Red-O Pulmonary and Respiratory Medicine Chest Pain medicine.medical_specialty ELP exogenous lipoid pneumonia Osteoarthropathy Primary Hypertrophic Pneumonia Viral Mycobacterium Infections Nontuberculous Lung biopsy Article 03 medical and health sciences Internal medicine Pneumonia Bacterial medicine Humans ALD adrenoleukodystrophy Tuberculosis Pulmonary NTM non-tuberculous mycobacteria business.industry Oxygen Inhalation Therapy biology.organism_classification Respiration Artificial Bronchoalveolar lavage Cough 030228 respiratory system Supportive psychotherapy Dietary Supplements Pediatrics Perinatology and Child Health Nasal Lavage ILD interstitial lung disease business MRI magnetic resonance imaging Constipation Oils PAS periodic acid schiff |
| Zdroj: | Paediatric Respiratory Reviews |
| ISSN: | 1526-0542 4201-7068 |
| Popis: | Objectives To describe the clinical-radiological-pathological characteristics and treatment outcomes of children with suspected exogenous lipoid pneumonia (ELP). Design Systematic review. We searched electronic databases and reference lists published between 1967 and 2018, restricted to non-accidental cases. Results Forty-four studies including 489 participants aged 1 day to 17 years from 13 countries were included. Cultural, medical, and behavioural rationale for oil-use was described. The clinical-radiological presentation varied widely. Diagnostic certainty was deemed highest if ELP was confirmed on bronchoalveolar lavage/frozen section lung biopsy with documented extracellular lipid on cytological staining and/or fat analysis. Non-tuberculous mycobacteria infection was identified in six studies: Mycobacterium fortuitum/chelonei, Mycobacterium smegmatis and Mycobacterium abscessus. Treatment comprised supportive therapy, corticosteroids, stopping oil, therapeutic lung-lavage and surgical resection. Outcomes were reported inconsistently. Conclusion Paediatric ELP resulting from cultural and medical practices continues to be described globally. Preventive interventions, standardized reporting, and treatment efficacy studies for cases not averted, are lacking. Protocol registration: PROSPERO CRD42017068313. |
| Databáze: | OpenAIRE |
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