A brief, highly selective history of acute phase proteins as indicators of infection, inflammation and injury
| Autor: | Elizabeth D. Moyer, Michael C. Powanda |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Allergy Immunology Acute phase proteins Inflammation Infections Chronic disease C-reactive protein 03 medical and health sciences 0302 clinical medicine Internal medicine Animal models of disease medicine Animals Humans Pharmacology (medical) Morbidity and mortality Pharmacology Innate immunity Innate immune system biology business.industry Vaccination Acute-phase protein medicine.disease Blood proteins Rheumatology Immunity Innate 030104 developmental biology Trauma and sepsis Acute Disease biology.protein Commentary Wounds and Injuries medicine.symptom business Covid-19 030217 neurology & neurosurgery Acute-Phase Proteins |
| Zdroj: | Inflammopharmacology |
| ISSN: | 1568-5608 0925-4692 |
| Popis: | There is an array of plasma protein alterations that occur in a wide variety of species, including humans in response to trauma, inflammation and infections, seemingly irrespective of etiologic agent. In numerous species, these plasma proteins are part of the innate immune response. In addition, it appears that a number of the plasma proteins in this array can be predictive of morbidity and/or mortality. We propose that based on historic use, selected acute phase proteins should be included in ongoing and future non-clinical and clinical studies to help us better understand disease progression in chronic, as well as acute diseases. In addition to assess if there is a relationship between vaccine-induced inflammation and degree of protection from live, attenuated or synthetic vaccines. |
| Databáze: | OpenAIRE |
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