Reference Intervals for Fetal Heart Volume From 3-Dimensional Sonography Using the Extended Imaging Virtual Organ Computer-Aided Analysis Method at Gestational Ages of 20 to 34 Weeks

Autor: E. Q. Barreto, Antonio Fernandes Moron, L. M. M. Nardozza, H.J. Milani, Araujo Júnior E, K. K. Haratz
Přispěvatelé: Universidade Federal de São Paulo (UNIFESP), Universidade de São Paulo (USP), Escola Ultrasonog & Reciclagem Med Ribeirao Preto, Inst Nacl Ciencia & Tecnol Hormonios & Saude Mulh
Rok vydání: 2012
Předmět:
Zdroj: Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
ISSN: 0278-4297
DOI: 10.7863/jum.2012.31.5.673
Popis: Objectives-The purpose of this study was to establish the reference range for fetal heart volume from 3-dimensional (3D) sonography using the extended imaging virtual organ computer-aided analysis method.Methods-The fetal heart volume was measured in 303 normal singleton pregnancies at gestational ages of 20 to 34 weeks using 3D sonography. The extended imaging virtual organ computer-aided analysis method was used to obtain a sequence of 10 parallel symmetric sections through the heart, according to examiner-determined limits (the apex at one extremity and the connection to the great vessels at the other). Heart contours were drawn manually in all sections to obtain the 3D volume measurement, which was provided automatically by the software. Normal z scores and percentile reference ranges for each gestational age were constructed.Results-The fetal heart volume increased with gestational age. The mean values were 3.09 mL at 20 weeks, 9.18 mL at 26 weeks, and 24.89 mL at 34 weeks, according to the following formulas: fetal heart volume (mL) = 18.0076 - 2.1005 x gestational age + 0.0677 x gestational age(2) (R-2=0.922); and SD (mL) = (4.5038 - 0.4281 x gestational age + 0.0114 x gestational age(2)) x root 1.495808 (R-2=0.922).Conclusions-A reference range for fetal heart volume using the 3D sonographic extended imaging virtual organ computer-aided analysis method at gestational ages of 20 to 34 weeks was established. Univ Fed Sao Paulo, Dept Obstet, BR-05303000 Sao Paulo, SP, Brazil Univ Fed Sao Paulo, Dept Obstet, BR-05303000 Sao Paulo, SP, Brazil Web of Science
Databáze: OpenAIRE