Donation after cardiac death: a 29-year experience

Autor: Jon S. Odorico, Hans W. Sollinger, Nilto C. De Oliveira, Silke V. Niederhaus, Joshua D. Mezrich, Robert B. Love, Nikole A. Neidlinger, Jim Kim, David P. Foley, Luis A. Fernandez, Philip Wai, Glen Leverson, Janet M. Bellingham, Anthony M. D'Alessandro, Chandrasekar Santhanakrishnan
Rok vydání: 2011
Předmět:
Zdroj: Surgery. 150(4)
ISSN: 1532-7361
Popis: Collaborative efforts in the transplant community as well as mandates from governmental agencies to increase organ donation are attempting to find solutions for the disparity between the availability of organs for transplant and the need. Centers for Medicare and Medicaid Services, Joint Commission on Accreditation of Healthcare Organizations (JCAHO), and United Network for Organ Sharing (UNOS) encouraged increasing donation after cardiac death (DCD).1 Despite these initiatives, the number of organs obtainable for transplant has declined in recent years.2 Over a 5-year period (2003–2008), the number of DCD donors has tripled nationwide; moreover, a growing portion of the total donors is from donation after cardiac death. The rate of DCD donors, which was 4% in 2003 increased to 11% by 2008.3 The rates of DCD donation at the University of Wisconsin organ procurement organization have been consistent over this period with DCD donors comprising 17–30% of total organ donors. In addition, recently available data demonstrates that organ recovery from DCD donors increased 24% between 2006 and 2007, compared with a decline of 2% for standard criteria donors (SCD).4 The increase in DCD donors has contributed to a utilization of additional younger donors, augmented total donors in the United States over the past decade, and although still not meeting the need of the numbers on transplant waiting lists, may have contributed to a stabilization of waitlist deaths.5 The purpose of this large single center study of the long-term outcomes of donation after cardiac death organs is meant to add to the data supporting DCD donation as a means to enhance the donor pool as well as reveal clinical challenges created by DCD allografts.
Databáze: OpenAIRE